product summary
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company name :
MyBioSource
product type :
antibody
product name :
mAb anti-Human Transferrin Receptor
catalog :
MBS592146
quantity :
0.5 mg
price :
430 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CY-TFR
reactivity :
human
application :
ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS592146
products type :
Antibody
products full name :
mAb anti-Human Transferrin Receptor
products short name :
Transferrin Receptor
products name syn :
Human Transferrin; Mouse monoclonal antibody (mAb) to human transferrin receptor or mAb to human cluster of differentiation 71 (CD71).
other names :
transferrin receptor; Transferrin receptor protein 1; transferrin receptor protein 1; transferrin receptor (p90, CD71); transferrin receptor; T9; p90; CD_antigen: CD71
other gene names :
TFRC; TFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR
uniprot entry name :
TFR1_HUMAN
clonality :
Monoclonal
isotype :
IgG1,k
clone :
CY-TFR
host :
Mouse
reactivity :
Human. Others not tested
sequence length :
760
specificity :
Reactive with human transferrin receptor. Human Transferrin
purity :
Protein G affinity purified
form :
Lyophilized from a solution in 0.01M PBS, pH 7.2
storage stability :
Store at -20 degree C
tested application :
ELISA (EIA)
other info1 :
Target Protein: Human transferrin receptor. Immunogen: Purified human transferrin receptor. Myeloma: Sp2/0-Ag14. Light Chain: Kappa. Reconstitution: Double distillated water is recommended to adjust the final concentration to 1.00mg/mL.
other info2 :
Research Area: Iron metabolism
products categories :
Primary antibodies; Monoclonal Antibodies to Leukocyte Surface Markers
products description :
Mouse monoclonal antibody to human Transferrin Receptor, Protein G affinity purified
ncbi gi num :
339516
ncbi acc num :
AAA61153.1
ncbi mol weight :
84,871 Da
ncbi pathways :
Clathrin Derived Vesicle Budding Pathway (119545); Endocytosis Pathway (102279); Endocytosis Pathway (102181); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Golgi Associated Vesicle Biogenesis Pathway (119546); HIF-1 Signaling Pathway (695200); HIF-1-alpha Transcription Factor Network Pathway (138045); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Iron Metabolism In Placenta Pathway (672461)
uniprot summary :
TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Protein type: Membrane protein, integral; Receptor, misc.; Cell surface. Chromosomal Location of Human Ortholog: 3q29. Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; integral to plasma membrane; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; membrane; perinuclear region of cytoplasm; melanosome; plasma membrane; endosome; vesicle; external side of plasma membrane. Molecular Function: identical protein binding; protein binding; transferrin receptor activity; double-stranded RNA binding. Biological Process: receptor-mediated endocytosis; viral reproduction; cellular iron ion homeostasis; positive regulation of bone resorption; transferrin transport; regulation of cell growth; osteoclast differentiation; transmembrane transport; regulation of cell proliferation
size1 :
0.5 mg
price1 :
430 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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