catalog number :
MBS592040
products full name :
mAb anti-Human GP IIb/IIIa
products short name :
GP IIb/IIIa
products name syn :
Platelet Membrane GPIIb-IIIa Complex; Mouse monoclonal antibody to human platelet membrane glycoprotein IIb/IIIa (GP IIb/IIIa)
products gene name :
GP IIb/IIIa
reactivity :
Human. Others not tested
specificity :
The mAb is reactive to platelet coated ELISA plate. Platelet Membrane GPIIb-IIIa Complex
purity :
Protein G affinity purified
form :
Lyophilized from a solution in 0.01M PBS, pH 7.2
storage stability :
Store at -20 degree C
tested application :
ELISA (EIA)
app notes :
ELISA: The mAb is reactive to platelet coated ELISA plate.
other info1 :
Target Protein: Human platelet membrane glycoprotein IIb/IIIa (GP IIb/IIIa). Immunogen: Human platelet suspension. Myeloma: Sp2/0-Ag14. Light Chain: Kappa. Reconstitution: Double distillated water is recommended to adjust the final concentration to 1.00mg/mL.
other info2 :
Research Area: Hematology, blood coagulation
products categories :
Primary antibody; Monoclonal Antibodies to Human Coagulation Factor
products description :
Human platelet membrane glycoprotein Glycoprotein llb/llla (Gp llb/llla) is a dominate receptor on the platelet membrane with very high molecular weight (>200kDa). After the platelet is activated, the GP llb/llla receptor complex changes conformation and binds to fibrinogen in blood circulation with high affinity. The activation of platelets is initiated locally when the endothelial layer is wounded and the platelets are exposed to the collagen underneath the endothelium. The fibrinogen aggregates with platelets when binding to the GP llb/llla receptor on platelets, thus primary haemostasis (Platelet clot) is formed.