Human IFN-gamma ELISpot Kit | MyBioSource MBS591002 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human IFN-gamma ELISpot Kit

catalog :

MBS591002

quantity :

96 Wells

price :

635 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS591002

products type :

ELISpot Kit

products full name :

Human IFN-gamma ELISpot Kit

products short name :

Human Interferon-Gamma (IFN-gamma) ELISpot

other names :

interferon-gamma; Interferon gamma; interferon gamma; IFN-gamma; immune interferon; OTTHUMP00000240111; interferon, gamma; Immune interferon

products gene name :

IFN-gamma

other gene names :

IFNG; IFNG; IFG; IFI

uniprot entry name :

IFNG_HUMAN

sequence length :

166

specificity :

Human Interferon-Gamma (IFN-gamma) ELISpot

products categories :

Human ELISpot Kit

products description :

For the quantitation of single cells releasing interferon-gamma (IFN-gamma)

ncbi gi num :

184639

uniprot acc num :

P01579

ncbi mol weight :

19,348 Da

ncbi pathways :

ATF-2 Transcription Factor Network Pathway (138006); African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Allograft Rejection Pathway (83123); Allograft Rejection Pathway (535); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Antigen Processing And Presentation Pathway (83074); Antigen Processing And Presentation Pathway (485); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993)

ncbi summary :

This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.

uniprot summary :

IFNG: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. Homodimer. Released primarily from activated T lymphocytes. Belongs to the type II (or gamma) interferon family. Protein type: Secreted; Secreted, signal peptide; Membrane protein, integral; Cytokine. Chromosomal Location of Human Ortholog: 12q14. Cellular Component: extracellular space; extracellular region; external side of plasma membrane. Molecular Function: interferon-gamma receptor binding; cytokine activity. Biological Process: positive regulation of isotype switching to IgG isotypes; positive regulation of nitric oxide biosynthetic process; positive regulation of osteoclast differentiation; positive regulation of interleukin-23 production; negative regulation of smooth muscle cell proliferation; apoptosis; positive regulation of interleukin-12 production; positive regulation of interleukin-6 biosynthetic process; negative regulation of epithelial cell differentiation; sensory perception of mechanical stimulus; positive regulation of killing of cells of another organism; negative regulation of transcription from RNA polymerase II promoter; positive regulation of interleukin-1 beta secretion; positive regulation of membrane protein ectodomain proteolysis; cell surface receptor linked signal transduction; positive regulation of MHC class II biosynthetic process; positive regulation of mesenchymal cell proliferation; positive regulation of cell proliferation; positive regulation of T cell proliferation; cell cycle arrest; defense response to virus; regulation of the force of heart contraction; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to drug; neutrophil chemotaxis; positive regulation of synaptic transmission, cholinergic; adaptive immune response; CD8-positive, alpha-beta T cell differentiation during immune response; negative regulation of myelination; unfolded protein response; response to virus; cytokine and chemokine mediated signaling pathway; defense response to protozoan; positive regulation of tumor necrosis factor production; humoral immune response; antigen processing and presentation; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of interleukin-12 biosynthetic process; positive regulation of chemokine biosynthetic process; negative regulation of interleukin-17 production; protein import into nucleus, translocation; defense response to bacterium; neutrophil apoptosis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of neuron differentiation; cell motility; regulation of insulin secretion. Disease: Hepatitis C Virus, Susceptibility To; Aplastic Anemia; Mycobacterium Tuberculosis, Susceptibility To; Tuberous Sclerosis 2; Human Immunodeficiency Virus Type 1, Susceptibility To

size1 :

96 Wells

price1 :

635 USD

more info or order :

MyBioSource product webpage