catalog number :
MBS590045
products type :
ELISA Kit
products full name :
Prostate Specific Antigen (PSA)
products short name :
Prostate Specific Antigen
other names :
prostate-specific antigen isoform 1 preproprotein; Prostate-specific antigen; prostate-specific antigen; P-30 antigen; gamma-seminoprotein; kallikrein-3; prostate specific antigen; semenogelase; seminin; kallikrein-related peptidase 3; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase
other gene names :
KLK3; KLK3; APS; PSA; hK3; KLK2A1
uniprot entry name :
KLK3_HUMAN
specificity :
Prostate Specific Antigen (PSA)
other info2 :
Sensitivity: <1 ng/mL. Assay Range: 1-80 ng/mL
products categories :
ELISA Kits for Human Tumor Markers
products description :
For the Quantitative Determination of Human Prostate-Specific Antigen (PSA) Concentrations in Serum
ncbi acc num :
NP_001639.1
ncbi gb acc num :
NM_001648.2
ncbi mol weight :
25,116 Da
ncbi pathways :
Androgen Receptor Signaling Pathway 198806!!Coregulation Of Androgen Receptor Activity Pathway 138085!!FOXA1 Transcription Factor Network Pathway 137979!!Metabolism Of Proteins Pathway 106230!!Pathways In Cancer 83105!!Prostate Cancer Pathway 755440!!Prostate Cancer Pathway 83111!!Prostate Cancer Pathway 523!!Regulation Of Androgen Receptor Activity Pathway 138027!!Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway 105908
ncbi summary :
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]