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company name :
MyBioSource
product type :
antibody
product name :
Alpha-Tubulin Cleaved By Caspase-6 Rabbit Polyclonal Antibody
catalog :
MBS588220
quantity :
0.05 mL
price :
435 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, immunohistochemistry
more info or order :
product information
catalog number :
MBS588220
products type :
Antibody
products full name :
Alpha-Tubulin Cleaved By Caspase-6 Rabbit Polyclonal Antibody
products short name :
[Alpha-Tubulin Cleaved By Caspase-6]
products name syn :
[a-Tubulin cleaved by casp 6]
clonality :
Polyclonal
host :
Rabbit
reactivity :
Bovine, Mouse, Human
specificity :
The antibody recognizes the sequence (EEVGVD) in tubulin protein. It is specific for Caspase 6 cleaved a-Tubulin. The antibody was tested in IHC and western blots of samples with Alzheimer disease (AD) (Bovine brain sample, human samples, cells lines, mice hippocampus and whole brains). When tested in null mice with IHC and WB, no immunoreactivity was observed.
form :
Lyophilized serum
storage stability :
Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconst ituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
tested application :
Immunohistochemistry (IHC), Western Blot (WB)
app notes :
If reconstituted with deionized water in 50 ul: WB 1:1000; IHC 1:1000. Optimal dilution has to be determined by the user.
other info1 :
Preservative: None. Target: Tubulin cleaved by caspase-6. Immunogen: EEVGVD peptide
products description :
Tubulin is the major constituent of microtubules. Microtubules are assembled from dimers of a-and p-tubulin. a-Tubulin cleaved by caspase-6 can be found in neurons, neurofibrillary tangles, neutrophil threads, and neuritic plaques in Alzheimer disease. a-Tubulin has been found to associate with the axonal microtubule-associated protein Tau, indicating that the cleavage of the functional a-Tubulin C-terminal domain by caspase-6 could alter the state of microtubules in neurons.
products references :
1. Klaiman G-Targets of caspase-6 activity in human neurons and Alzheimer disease.
size1 :
0.05 mL
price1 :
435 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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