product summary
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company name :
MyBioSource
product type :
antibody
product name :
Polyclonal antibody to human occludin
catalog :
MBS584484
quantity :
0.1 mg
price :
520 USD
clonality :
polyclonal
host :
guinea pigs
conjugate :
nonconjugated
reactivity :
mouse, rat, dog
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS584484
products type :
Antibody
products full name :
Polyclonal antibody to human occludin
products short name :
[Occludin]
other names :
[occludin; Occludin; occludin]
other gene names :
[OCLN; OCLN]
uniprot entry name :
OCLN_CANFA
clonality :
Polyclonal
isotype :
Guinea pig Ig
host :
Guinea pig
reactivity :
Reactivity: Human. Cross reactivity: Canine, Mouse, Rat
sequence length :
521
form :
1 ml (100 ug/ml) 0.2 um filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
storage stability :
Product should be stored at 4 degree C. Under recommended storage conditions, product is stable for one year.
tested application :
Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot
app notes :
Application Use: For immunohistology, immunfluorescence and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
other info1 :
Species: Guinea pig Ig
other info2 :
Other recommended product: MBS584478: Polyclonal antibody against Human ZO-1. MBS584473: Polyclonal antibody against Human ZO-1 alpha-plus. MBS584512: Polyclonal antibody against Human ZO-1 alpha-minus. MBS584514: Polyclonal antibody against Human ZO-2. MBS584196: Monoclonal antibody against Human JAM-A (JAM-1), clone M.Ab. F11
products description :
Product Description: The polyclonal antibody reacts with human occludin, an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1). The antibody is generated against recombinant human occludin (aa 358-504). The polyclonal anti-human occludin antibody cross reacts with rat, mouse and dog occludin.
products references :
Van Itallie, C et al; Occludin confers adhesiveness when expressed in fibroblasts. J Cell Sci 1997, 110: 1113.
ncbi gi num :
50978954
ncbi acc num :
NP_001003195.1
ncbi gb acc num :
NM_001003195.1
ncbi mol weight :
59,275 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway (84119); Cell Adhesion Molecules (CAMs) Pathway (480); Hepatitis C Pathway (173976); Hepatitis C Pathway (173907); Leukocyte Transendothelial Migration Pathway (84133); Leukocyte Transendothelial Migration Pathway (494); Tight Junction Pathway (84121); Tight Junction Pathway (482)
uniprot summary :
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Interacts with ZO-1.
size1 :
0.1 mg
price1 :
520 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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