product summary
Loading...
company name :
MyBioSource
product type :
other
product name :
Trametinib (GSK1120212)
catalog :
MBS576333
quantity :
10 mg
price :
145 USD
more info or order :
image
image 1 :
product information
catalog number :
MBS576333
products type :
Inhibitor
products full name :
Trametinib (GSK1120212)
products short name :
[Trametinib]
storage stability :
2 Years -80°C in solvent. 3 years -20°C powder.
image1 heading :
Structure
other info1 :
CAS: 871700-17-3. Molecular Formula: C 26 H 23 FIN 5 O 4 . Solubility: DMSO 22 mg/mL(35.75 mM). Water <1 mg/mL. Target: MEK2 1.8nM. MEK1 0.92nM. Analytical Data: *NMR: 1H NMR spectrum of sample consistens with structure of the compound;. *HPLC: sample tested with high performance liquid chromatography purity 99.39%
products description :
Trametinib is an orally bioavailable inhibitor of mitogen-activated protein kinase kinase (MEK MAPK/ERK kinase) with potential antineoplastic activity. Trametinib specifically binds to and inhibits MEK 1 and 2, resulting in an inhibition of growth factor-mediated cell signaling and cellular proliferation in various cancers. MEK 1 and 2, dual specificity threonine/tyrosine kinases often upregulated in various cancer cell types, play a key role in the activation of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth.
ncbi mol weight :
615.39
size1 :
10 mg
price1 :
145 USD
size2 :
1ml/10mM (in DMSO)
price2 :
145
size3 :
50 mg
price3 :
165
size4 :
100 mg
price4 :
200
size5 :
200 mg
price5 :
240
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
browse more products
questions and comments