catalog number : 
MBS570017
products full name : 
Mouse anti Neu-Oncogen (C-erb B2)
products short name : 
Neu-Oncogen (C-erb B2)
specificity : 
CB11 is specific for Neu-(c-erbB-2) protein.
form : 
Each vial contains 1 ml of culture supernatant of monoclonal antibody containing 0.09% sodium azide.
storage stability : 
Store undiluted antibody at 4 degree C. For prolonged storage: store aliquots at -20 degree C.
tested application : 
Immunocytochemistry (IHC), Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin)
app notes : 
CB11is suitable for immunocytochemistry and immunohistochemistry on frozen and paraffin-embedded (without pretreatment) tissue sections. Recommended dilution is 1:5 - 1:10. Dilute immediately before use with PBS or Tris.
other info1 : 
Source Note: CB11 is a IgG1 Mouse monoclonal antibody derived by fusion of p3-NS1Mouse myeloma cells with spleen cells from a BABL/c Mouse immunized with a synthetic peptide.
products categories : 
Tumour marker
products description : 
C-erbB-2 oncogene codes for a membrane protein, Neu-(c-erbB-2) protein. In several studies the amplifiCation of C-erbB-2 oncogene in carcinomas has been reported. Overexpression of the Neu-oncogene protein can be demonstRated by this monoclonal antibody. Immunoblotting: the antibody is reactive with a 185 kD protein.
products references : 
Vijver van de M.J., et al. Immunohistochemical detection of the neu-protein in tissue sections of Human breast tumors with amplified neu-DNA (1988). Oncogene 2, 175-178. Flack V.G., et al. C-erb-B-2 oncogene product staining in gastric Adenocarcinoma. An Immunohistochemical study (1989). Journal of Pathology, 159, 107-111.