other

Alpha-fetoprotein (AFP) Antigen >40%

MBS568855

1 mg

280 USD

Antigen

Alpha-fetoprotein (AFP) Antigen >40%

[Alpha-fetoprotein (AFP)]

[alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin]

[AFP]

[AFP; AFP; AFPD; FETA; HPAFP; HPAFP]

FETA_HUMAN

Cord Serum

609

>=40% AFP by SDS-PAGE

Liquid

7.8 mg/ml

Store at 2-8°C

Control Grade

Preservative: 0.05% Sodium Azide. Supplied In: 10mM Phosphate Buffered Saline, pH 7.2-7.4. Comments: Tested negative for HBsAg, antibodies to HCV and HIV 1/2

Tumor Markers

4501989

NP_001125.1

NM_001134.2

Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]

AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: cytoplasm; extracellular space. Molecular Function: metal ion binding. Biological Process: liver development; organ regeneration; ovulation from ovarian follicle; pancreas development; progesterone metabolic process; response to organic substance; transport. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of

1 mg

280 USD