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Vitamin D Binding Protein >=95%

MBS568853

2 mg

385 USD

Antigen

Vitamin D Binding Protein >=95%

[Vitamin D Binding Protein]

[vitamin D-binding protein isoform 1; Vitamin D-binding protein; vitamin D-binding protein; group-specific component (vitamin D binding protein); Gc protein-derived macrophage activating factor]

[GC; GC; DBP; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; HEL-S-51; DBP-maf]

VTDB_HUMAN

Human Plasma

474

> 95%

Lyophilized from 20 mM NaH 2 PO 4 , 0.15 M NaCl, pH 7.4

Ships on blue ice. Upon receipt, store at -20°C.

Immunogen Grade

Comments: Centrifuge briefly prior to opening. Reconstitute with 250 uL of deionized water and swirl or vortex to mix. If further dilution is necessary use lyophilization buffer. Testing: Shown to be non reactive for HBsAg, anti-HCV, anti-Hcv, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Serum Proteins

32483410

NP_000574.2

NM_000583.3

Metabolism Pathway (1269956); Metabolism Of Fat-soluble Vitamins Pathway (1339147); Metabolism Of Vitamins And Cofactors Pathway (1270144); Vitamin D (calciferol) Metabolism Pathway (1270052); Vitamin D Synthesis Pathway (198764)

The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

GC: Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 4q12-q13. Cellular Component: axon; cytosol; extracellular region; extracellular space; lysosomal lumen; perinuclear region of cytoplasm. Molecular Function: actin binding; vitamin D binding; vitamin transporter activity. Biological Process: female pregnancy; lactation; response to estradiol stimulus; response to nutrient levels; vitamin D metabolic process; vitamin transport. Disease: Graves Disease, Susceptibility To, 1

2 mg

385 USD