product summary
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company name :
MyBioSource
product type :
other
product name :
Myeloperoxidase (MPO) Antigen >96%
catalog :
MBS568668
quantity :
1 mg
price :
710 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS568668
products type :
Antigen
products full name :
Myeloperoxidase (MPO) Antigen >96%
products short name :
[Myeloperoxidase (MPO)]
other names :
[myeloperoxidase; Myeloperoxidase; myeloperoxidase; myeloperoxidase]
products gene name :
[MPO]
other gene names :
[MPO; MPO; MPO]
uniprot entry name :
PERM_HUMAN
host :
Human Neutrophil
sequence length :
745
purity :
>=96%
form :
Liquid
concentration :
1.6mg/ml
storage stability :
Store at 2-8 degree C
tested application :
ELISA (EIA), Western Blot (WB)
other info2 :
Supplied In: 50 mM Sodium Acetate, pH 6.0 with NaCl
products categories :
Cardiac Markers
ncbi gi num :
188658
ncbi acc num :
AAA59863.1
ncbi pathways :
C-MYB Transcription Factor Network Pathway (138073); Folate Metabolism Pathway (198833); IL23-mediated Signaling Events Pathway (138000); Phagosome Pathway (153910); Phagosome Pathway (153859); Selenium Pathway (198825); Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987); Vitamin B12 Metabolism Pathway (920974); Amb2 Integrin Signaling Pathway (137945)
ncbi summary :
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
uniprot summary :
MPO: Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Homodimer; disulfide-linked. Each monomer consists of a light and a heavy chain. Belongs to the peroxidase family. XPO subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.11.2.2; Oxidoreductase. Chromosomal Location of Human Ortholog: 17q23.1. Cellular Component: azurophil granule; extracellular space; lysosome; nucleus; secretory granule. Molecular Function: chromatin binding; heparin binding; peroxidase activity. Biological Process: defense response; defense response to bacterium; hydrogen peroxide catabolic process; negative regulation of apoptosis; response to oxidative stress. Disease: Alzheimer Disease; Myeloperoxidase Deficiency
size1 :
1 mg
price1 :
710 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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