product summary
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company name :
MyBioSource
product type :
antibody
product name :
FMRFamide polyclonal antibody
catalog :
MBS565342
quantity :
0.025 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS565342
products type :
Antibody
products full name :
FMRFamide polyclonal antibody
products short name :
[FMRFamide]
products name syn :
[Phe-Met-Arg-Phe-amide]
other names :
[Pro-FMRFamide-related neuropeptide FF; Pro-FMRFamide-related neuropeptide FF; pro-FMRFamide-related neuropeptide FF; neuropeptide FF-amide peptide precursor; FMRFamide-related peptides]
products gene name :
[Phe-Met-Arg-Phe-amide]
other gene names :
[NPFF; NPFF; FMRFAL; NPSF; NPFF; NPAF]
uniprot entry name :
NPFF_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Species Independent
sequence length :
113
specificity :
Recognizes FMRF in multiple species including human.
form :
Liquid. Neat serum containing 0.1% sodium azide.
storage stability :
Long term storage: -20 degree C. Shipping: Ships on Blue Ice.
tested application :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic FMRF-amide (Phe-Met-Arg-Phe-amide).
other info2 :
Host Note: Whole rabbit serum.
products categories :
Cell Signaling
ncbi gi num :
8134595
ncbi acc num :
O15130.1
uniprot acc num :
O15130
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); G Alpha (q) Signalling Events Pathway (1269578); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1269592); Orexin And Neuropeptides FF And QRFP Bind To Their Respective Receptors Pathway (1269550); Peptide Ligand-binding Receptors Pathway (1269546); Signal Transduction Pathway (1269379); Signaling By GPCR Pathway (1269543)
ncbi summary :
This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
uniprot summary :
NPFF: Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels. Belongs to the FARP (FMRFamide related peptide) family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 12q13.13. Cellular Component: cytosol; dendrite; extracellular region; extracellular space; nerve terminal; perikaryon; vesicle. Molecular Function: G-protein-coupled receptor binding; neuropeptide hormone activity; receptor binding. Biological Process: acute inflammatory response to antigenic stimulus; elevation of cytosolic calcium ion concentration; maternal process involved in pregnancy; negative regulation of appetite; negative regulation of heart rate; negative regulation of insulin secretion; neuropeptide signaling pathway; positive regulation of blood pressure; regulation of excitatory postsynaptic membrane potential; regulation of sensory perception of pain; response to drug; response to morphine; spinal cord development; synaptic transmission; vasopressin secretion
size1 :
0.025 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
460
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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