product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anthrax Protective Antigen monoclonal antibody (PA6)
catalog :
MBS565142
quantity :
0.1 mg
price :
370 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
anthrax
application :
western blot, ELISA, immunoprecipitation, enzyme immunoassay
more info or order :
product information
catalog number :
MBS565142
products type :
Antibody
products full name :
Anthrax Protective Antigen monoclonal antibody (PA6)
products short name :
[Anthrax Protective Antigen]
other names :
[Protective antigen; Protective antigen; pXO1-110; Anthrax toxins translocating protein; PA-83; PA83]
other gene names :
[pxo1_110; pagA; pag; PA; PA83; PA20; PA63]
uniprot entry name :
PAG_BACAN
clonality :
Monoclonal
isotype :
IgG1
host :
Mouse
reactivity :
Bacillus anthracis
sequence length :
764
specificity :
Recognizes bacteria Anthrax Protective Antigen (PA).
purity :
Protein G affinity purified.
form :
Liquid. In PBS containing 0.01% sodium azide.
concentration :
1 mg/ml
storage stability :
Long term storage: -20°C. Avoid freeze/thaw cycles. Ships on blue ice.
tested application :
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
other info1 :
Immunogen: Anthrax protective antigen. Source: Purified from hybridoma tissue culture supernatant.
products categories :
Bacteria & Viruses
products description :
The exotoxin produced by B. anthracis is composed of three proteins: a cell-receptor binding protein known as Protective Antigen (PA), and two enzymes, Edema Factor (EF) and Lethal Factor (LF). An 83 kDa form of PA binds to a cell surface receptor and, upon proteolytic activation to a 63 kDa fragment, heptamerizes to form a membrane channel that mediates the entry of three molecules of LF or EF into the cells. PA and LF form Lethal Toxin, which is the dominant virulence factor produced by B. Anthracis and is the major cause of death in infected animals.
ncbi gi num :
17380160
ncbi acc num :
P13423.2
uniprot acc num :
P13423
ncbi pathways :
Cellular Roles Of Anthrax Toxin Pathway (138076); Disease Pathway (1268854); Infectious Disease Pathway (1269056); Uptake And Actions Of Bacterial Toxins Pathway (1269144); Uptake And Function Of Anthrax Toxins Pathway (1269154)
uniprot summary :
One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
size1 :
0.1 mg
price1 :
370 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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