antibody

Affinity Purified Rabbit anti-Calmodulin Binding Protein Tag

MBS560452

1 mg

730 USD

polyclonal

rabbit

nonconjugated

Antibody

Affinity Purified Rabbit anti-Calmodulin Binding Protein Tag

anti-Calmodulin Binding Peptide

Affinity Purified Rabbit anti-Calmodulin Binding Peptide

calmodulin; Calmodulin; calmodulin; caM; OTTHUMP00000164793; OTTHUMP00000164794; calmodulin 3 (phosphorylase kinase, delta)

CALM3; CALM1; PHKD; CALM1; CALM2; PHKD3; CALM; CAM; CAM1

CALM_HUMAN

Polyclonal

Rabbit

Unconjugated A.P.

Liquid

Store at 4 degree C. Shelf Life: 12 months after shipment date.

ELISA Coating: 1.0 - 5.0 ug/mL Western Blot: 1.0 - 0.1 ug/mL

Buffer: Phosphate buffered saline, pH 7.2

Preservative: 0.1% sodium azide. Procedure: Rabbits were immunized with Calmodulin Binding Protein (CBP) epitope tag (MKRRWKKNFIAVSAANRFKKISSSGAL) conjugated with KLH. After multiple immunizations in Freunds adjuvant, serum was collected. Antibodies were immunoaffinity purified using the peptide immobilized on a solid phase.

Epitope Tag

Rabbits were immunized with synthetic peptide corresponding to the Calmodulin Binding Protein (CBP) epitope tag conjugated to a carrier protein. The resulting antiserum was passed over an antigen containing immunoabsorbant from which the anti-CBP was immunoaffinity purified.

825635

P62158

16,838 Da

Activation Of Ca-permeable Kainate Receptor Pathway 161046!!Activation Of CaMK IV Pathway 161042!!Activation Of Kainate Receptors Upon Glutamate Binding Pathway 161043!!Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway 161033!!Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!BCR Signaling Pathway 138058!!CREB Phosphorylation Through The Activation Of CaMKII Pathway 161040!!CREB Phosphorylation Through The Activation Of CaMKK Pathway 161041!!CREB Phosphorylation Through The Activation Of Ras Pathway 161036

Function: Calmodulin mediates the control of a large number of enzymes and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Ref.21. Subunit structure: Interacts with MYO1C and RRAD. By similarity. Interacts with CEP97, CEP110, TTN/titin and SRY. Interacts with USP6; the interaction is calcium dependent. Interacts with CDK5RAP2. Ref.16 Ref.17 Ref.18 Ref.19 Ref.21 Ref.22 Ref.31. Subcellular location: Cytoplasm cytoskeleton spindle. Cytoplasm cytoskeleton spindle pole. Note: Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules. Ref.21. Post-translational modification: Ubiquitination results in a strongly decreased activity. By similarity.Phosphorylation results in a decreased activity. Miscellaneous: This protein has four functional calcium-binding sites. Sequence similarities: Belongs to the calmodulin family.Contains 4 EF-hand domains. Sequence caution: The sequence CAA36839.1 differs from that shown. Reason: Erroneous gene model prediction.

1 mg

730 USD