antibody

Affinity Purified Goat anti-Human Alpha Fetoprotein

MBS560255

1 mg

470 USD

polyclonal

goat

nonconjugated

Antibody

Affinity Purified Goat anti-Human Alpha Fetoprotein

Alpha Fetoprotein

Affinity PurifiedGoat anti-Human Alpha Fetoprotein; anti-Human Alpha Fetoprotein

alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; OTTHUMP00000220440; alpha-fetoglobulin; alpha-1-fetoprotein; alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin

AFP; AFP; FETA; HPAFP; AFP; HPAFP

FETA_HUMAN

Polyclonal

Goat

Human

Unconjugated A.P.

Liquid

Store at 4 degree C. Shelf Life: 12 months after shipping date

This product has been qualified by ELISA, immunoelectrophoresis and gel diffusion techniques.

Buffer: Phosphate buffered saline, pH 7.2

Preservative: 0.1% sodium azide. Procedure: Goats were immunized with highly purified human alpha fetoprotein in Freund's adjuvant. The antiserum was solid phase absorbed to ensure it is monospecific to human alpha fetoprotein then immunoaffinity purified off an antigen containing immunoabsorbant.

Human Protein

Goats were immunized with highly purified human alpha-fetoprotein. The resulting antiserum was passed over an antigen containing immunoabsorbant from which the anti-human alpha-fetoprotein was immunoaffinity purified.

178236

P02771

68,678 Da

Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014)

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq]

AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; cytoplasm. Molecular Function: metal ion binding. Biological Process: transport; progesterone metabolic process; ovulation from ovarian follicle. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of

1 mg

470 USD