antibody

Laminin 111, Affinity Purified, Rabbit

MBS555738

0.1 mL

405 USD

polyclonal

rabbit

nonconjugated

western blot, immunohistochemistry, immunocytochemistry

Antibody

Laminin 111, Affinity Purified, Rabbit

[Laminin 111]

Polyclonal

Rabbit

Mouse

Affinity purified antibody

Liquid

1.0 mg/mL

Antibody can also be aliquotted and stored frozen at -20°C to -70°C in a manual defrost freezer for six months without detectable loss of activity. The antibody can be stored at 2-8°C for 1 month without detectable loss of activity. Avoid repeated freeze thaw cycles.

Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

Immunofluorescence/Immunohistochemistry: 1:100-5000. Western Blot: 1:10000-5000. Dilutions listed as recommendation. Optimal dilutions should be determined by investigator.

Testing Data

Western Blot (WB) (WB)

Immunogen Sequence: Laminin-111 isolated from mouse EHS cells . HGNC name : LAMA1, LAMB1, LAMC1

Laminins are high-molecular weight (~400kDa) proteins of the extracellular matrix. They are an important and biologically active part of the basal lamina, which is one of the layers of the basement membrane, a protein network foundation for most cells and organs, influencing cell differentiation, migration, and adhesion. Laminins are heterotrimeric proteins that contain an alpha-chain, a beta-chain, and a gamma-chain. The distribution of the different laminin isoforms is tissue-specific. The laminin molecules are named according to their chain composition. Laminin-111 is one of the first laminin isoforms to be discovered. The "111" identifies the isoform's chain composition of alpha1beta1gamma1. Laminin-111 is predominantly expressed in the embryonic epithelium, but can also be found in some adult epithelium such as the kidney,liver, testis, ovaries, and brain blood vessels. Laminin-111 has been identified as a crucial molecule for development of the embryo, genetic ablation of laminin-111 results in embryonic death.

0.1 mL

405 USD