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NPY Y2 Receptor, Control Peptide

MBS555329

0.05 mL

175 USD

Antibody

NPY Y2 Receptor, Control Peptide

[NPY Y2 Receptor]

[neuropeptide Y receptor type 2; Neuropeptide Y receptor type 2; neuropeptide Y receptor type 2; neuropeptide Y receptor Y2; NPY-Y2 receptor; Y2 receptor]

[NPY Y2]

[NPY2R; NPY2R; NPY2-R; NPY2-R; Y2 receptor]

NPY2R_HUMAN

Mouse, Rat

381

TDSFSEATNV

Liquid-50 ul. Concentration of 2 mgs/ml.

For maximum stability, the peptide at - 20 degree C. Most peptides will be stable in solution for several days at 4 degree C. Avoid repeated freeze/thaws.

Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

Used for absorption control of antiserum binding. Antibody should be pre-incubated withpeptide prior to incubation with tissue/sample. We suggest pre-Incubation for 1 hour at room temperature. A 10 -6 or 10 5 molar (M) peptide concentration is suggested to block antigen/antibody binding. However, optimal working concentration should be determined by the investigator using a range of peptide dilutions to eliminate or reduce immunoreactivity.

Testing Data

Testing Data

Product Type: Peptide

Antibodies; Pain and Inflammation; NPY Y2 Receptor

Control Antigen for use in absorption control

4505447

NP_000901.1

NM_000910.3

1069

Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); G Alpha (i) Signalling Events Pathway (1269576); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Peptide GPCRs Pathway (198897); Peptide Ligand-binding Receptors Pathway (1269546); Signal Transduction Pathway (1269379)

NPY2R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY NPY PYY (3-36) NPY (2-36) [Ile-31, Gln-34] PP [Leu- 31, Pro-34] NPY PP, [Pro-34] PYY and NPY free acid. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 4q31. Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane. Molecular Function: peptide YY receptor activity; protein binding; calcium channel regulator activity; neuropeptide Y receptor activity; receptor activity. Biological Process: positive regulation of dopamine secretion; secretion; positive regulation of cell adhesion; behavioral fear response; negative regulation of synaptic transmission, glutamatergic; locomotory behavior; positive regulation of peptide secretion; elevation of cytosolic calcium ion concentration; negative regulation of cAMP biosynthetic process; neuropeptide signaling pathway; negative regulation of secretion; regulation of sensory perception of pain; G-protein signaling, adenylate cyclase inhibiting pathway; positive regulation of smooth muscle contraction; negative regulation of neurological process; positive regulation of circadian sleep/wake cycle, non-REM sleep; nitric oxide mediated signal transduction

0.05 mL

175 USD