catalog number :
MBS555079
products full name :
TGF beta, Monoclonal Antibody, Mouse
products short name :
TGF beta
other names :
transforming growth factor beta-1; Transforming growth factor beta-1; transforming growth factor beta-1; transforming growth factor beta 1; TGF-beta-5
products gene name :
TGF beta
other gene names :
tgfb1; tgfb1; ced; lap; dpd1; tgfb; tgfb5; tgfbeta; tgf-beta; TGF-beta5; TGF-beta-1
uniprot entry name :
TGFB1_XENLA
form :
Supernatant - Liquid
tested application :
Immunohistochemistry (IHC)
other info1 :
Type Info: Mouse IgM
other info2 :
Immunogen: Prokaryotic recombinant protein corresponding to the full length mature transforming growth factor beta1 molecule.
products categories :
Antibodies; Stem Cell Research Antibodies; TGF beta
products description :
Transforming growth factor beta (TGFB) inhibits cell proliferation and stimulates cell differentiation. This is achieved through a receptor complex of types I and II TGFB receptors. The type II receptor is a transmembrane serine/threonine kinase which is able to bind TGFB and transactivate the type I receptor. TGFB receptors are found in all myometrial tissues and, in the kidney, they are found exclusively in renal tubular cells. In normal gastric mucosa, type I and II receptors are demonstrated in fundic glands, but not on surface mucous cells and in normal small bowel and colon, TGFB receptors are expressed in the epithelial cells of the upper crypts.
ncbi acc num :
NP_001081330.1
ncbi gb acc num :
NM_001087861.1
ncbi mol weight :
44,201 Da
ncbi pathways :
AGE-RAGE Signaling Pathway In Diabetic Complications (1320296); AGE-RAGE Signaling Pathway In Diabetic Complications (1319775); Cell Cycle Pathway (84649); Cell Cycle Pathway (463); Cytokine-cytokine Receptor Interaction Pathway (119282); Cytokine-cytokine Receptor Interaction Pathway (460); Endocytosis Pathway (102271); Endocytosis Pathway (102181); FoxO Signaling Pathway (921596); Intestinal Immune Network For IgA Production Pathway (128758)