catalog number :
MBS553126
products type :
Recombinant Protein
products full name :
Epstein-Barr Virus Capsid Antigen BFRF3 Recombinant
products short name :
Epstein-Barr Virus Capsid Antigen BFRF3
products name syn :
hhv4; hhv-4; ebv; epstein barr; BFRF3; vca; capsid; vp26
other names :
BFRF3; Capsid protein VP26
products gene name :
EBV BFRF3
uniprot entry name :
VP26_EBVB9
purity :
>95%, as determined by SDS-PAGE.
form :
Lyophilized from 25mM Tris-Hcl pH 7.2, 1mM EDTA and 50% glycerol.
storage stability :
The lyophilized protein is stable for at least 2 years from date of receipt at -20 degree C. Upon reconstitution, this protein can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
app notes :
Recombinant human EBV p18 antigen is suitable for ELISA and Western blots, excellent antigen for detection of EBV with minimal specificity problems.
other info1 :
Host Note: DNA sequence encoding immunodominant fragment of Epstein-Barr Virus capsid BFRF3 protein expressed in Escherichia Coli.
other info2 :
Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Molecular Weight Note: Recombinant EBV p18 encodes the immunodominant sequences of theEpstein-Barr Virus capsid p18 protein. This molecule has a calculated mass of approximately 13kDa. Recombinant EBV p18 contains an N terminal GST purification tag and migrates as an approximately 39 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE.
products categories :
Viral Antigens
products description :
There are 11 known antigenically distinct glycoproteins in herpes simplex virus type 1 (HSV-1) virions: gB, gC, gD, gE, gG, gI, gH, gJ, gK, gL, and gM. These glycoproteins are the primary inducers and targets of humoral immune responses in HSV infection and are also important inducers and targets of cell-mediated immune responses. In addition, some of the HSV glycoproteins have been shown to interact with specific components of the immune system. Most immunological and vaccine studies of the HSV-1 glycoproteins have focused on gD and/or gB. This is at least partially due to the fact that these are the most abundant HSV glycoproteins and therefore were the first two glycoproteins to be expressed and to be shown to provide protection against HSV infection in animal models.
ncbi acc num :
YP_401651.1
ncbi gb acc num :
NC_007605.1
ncbi mol weight :
18,147 Da
ncbi pathways :
Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Salmonella Infection Pathway 375172!!Salmonella Infection Pathway 375149
uniprot summary :
Subcellular location: Virion . Potential. Sequence caution: The sequence CAA24838.1 differs from that shown. Reason: Erroneous initiation.