catalog number :
MBS553021
products type :
Recombinant Protein
products full name :
Human HIV-1 gp160 Recombinant
products short name :
HIV-1 gp160
products name syn :
hiv1; gp160
products gene name :
HIV1 gp160
products gene name syn :
HIV-1 gp160
specificity :
Immunoreactive with sera of infected HIV individuals
purity :
>90%, as determined by SDS-PAGE.
form :
Lyophilized from Imidasole 20mM, pH 7.0; DTT 10mM; NaCl 150mM; urea 8M
storage stability :
Upon reconstitution, this protein can be stored in working aliquots at 2-8 degree C for one month, or at -20 degree C for 12 months with detectable loss of activity.
app notes :
HIV1 gp160 antigen is suitable for ELISA and Western blots, excellent antigen for detection of HIV with minimal specificity problems.
other info1 :
Host Note: DNA sequence encoding immunodominant fragment of HIV-1 gp160 was expressed in Escherichia Coli.
other info2 :
Molecular Weight Note: Recombinant HIV-1 gp160 encodes the immunodominant sequences of the HIV surface Glycoprotein 160. Recombinant HIV gp160 is fused to an beta-galactosidase purification tag and migrates as 58kDa on PAGE. Endotoxin: Less than 0.1EU/ug as determined by LAL method
products categories :
Viral Antigens
products references :
structure-function analysis of HIV-1 gp120 amino acid mutations associated with resistance to the ccr5 co-receptor antagonist vicriviroc . J. Virol., Sep 2009; 10.1128/JVI.01351-09. HIV-1 gp120 -induced migration of dendritic cells is regulated by a novel kinase cascade involving pyk2, p38 map kinase and lsp1 . Blood, Aug 2009; 10.1182/blood-2009-02-206342. x4 HIV-1 gp120 down-modulates expression and immunogenicity of co-delivered antigens . J. Virol., Aug 2009; 10.1128/JVI.00394-09. llama antibody fragments with cross-subtype human immunodeficiency virus type 1 (hiv-1) -neutralizing properties and high affinity for HIV-1 gp120 . J. Virol., Dec 2008; 82: 12069 - 12081. cannabinoids inhibit HIV-1 gp120 -mediated insults in brain microvascular endothelial cells . J. Immunol., Nov 2008; 181: 6406 - 6416.