Mouse MIF Affinity Purified Polyclonal | MyBioSource MBS551195 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse MIF Affinity Purified Polyclonal

catalog :

MBS551195

quantity :

0.05 mg

price :

260 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS551195

products type :

Antibody

products full name :

Mouse MIF Affinity Purified Polyclonal

products short name :

[MIF]

products name syn :

[RAA25032; polyclonal; MIF]

other names :

[MIF; Macrophage migration inhibitory factor; macrophage migration inhibitory factor; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase; macrophage migration inhibitory factor (glycosylation-inhibiting factor); Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase (EC:5.3.3.12); Phenylpyruvate tautomerase]

products gene name :

[MIF]

other gene names :

[MIF; MIF; GIF; GLIF; MMIF; GLIF; MMIF; MIF; GIF]

uniprot entry name :

MIF_HUMAN

clonality :

polyclonal

isotype :

Rabbit IgG

host :

rabbit

reactivity :

Mouse

purity :

Purification: Serum IgG fraction was purified by affinity chromatography using immobilized recombinant mouse MIF. Purity: >95%

form :

Sterile filtered PBS pH 7.4 solution and %5 trehalose.

concentration :

0.2mg/ml

storage stability :

This antibody can be stored in working aliquots at 2 - 8 degree C for one month, or at -20 degree for six months without detectable loss of activity. Avoid repeated freeze/thaw cycles.

tested application :

Western Blot (WB), ELISA

app notes :

Western Blot (WB): Used at a concentration range of 2-10 ug/ml, with proper secondary antibody. ELISA: Antibody detection limit is 0.04ng/well using recombinant Mouse MIF (MBS553301). Use at a concentration range of 0.1-0.2 ug/mL with proper secondary antibody.

other info1 :

Host Note: Polyclonal Mouse MIF antibody was produced from sera of rabbits immunized with recombinant Mouse MIF

other info2 :

Presentation: Sterile solution from 0.2um filtered solution in PBS pH 7.4. Dilution: A quick spin of the vial followed by reconstitution in PBS pH 7.4 or other diluents.

products categories :

Antigen affinity polyclonals

ncbi gi num :

47678571

ncbi acc num :

CAG30406.1

uniprot acc num :

P14174

ncbi mol weight :

12,476 Da

ncbi pathways :

Adipogenesis Pathway (198832); Phenylalanine Metabolism Pathway (82960); Phenylalanine Metabolism Pathway (327); Spinal Cord Injury Pathway (739007); Tyrosine Metabolism Pathway (82959); Tyrosine Metabolism Pathway (325)

ncbi summary :

This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]

uniprot summary :

MIF: a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. Also acts as a phenylpyruvate tautomerase. Protein type: EC 5.3.2.1; Apoptosis; Cytokine; EC 5.3.3.12; Cell development/differentiation; Isomerase; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - phenylalanine. Chromosomal Location of Human Ortholog: 22q11.23. Cellular Component: nucleoplasm; extracellular space; cell surface; cytoplasm; extracellular region; vesicle. Molecular Function: phenylpyruvate tautomerase activity; protein binding; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; cytokine activity; dopachrome isomerase activity; receptor binding; chemoattractant activity. Biological Process: DNA damage response, signal transduction by p53 class mediator; regulation of macrophage activation; positive regulation of lipopolysaccharide-mediated signaling pathway; carboxylic acid metabolic process; cell aging; negative regulation of cellular protein metabolic process; prostaglandin biosynthetic process; positive regulation of peptidyl-serine phosphorylation; cell proliferation; positive regulation of MAP kinase activity; negative regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of fibroblast proliferation; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of myeloid cell apoptosis; cell surface receptor linked signal transduction; negative regulation of mature B cell apoptosis; positive chemotaxis; positive regulation of B cell proliferation; innate immune response; inflammatory response; positive regulation of phosphorylation; negative regulation of apoptosis; positive regulation of cytokine secretion. Disease: Rheumatoid Arthritis, Systemic Juvenile

size1 :

0.05 mg

price1 :

260 USD

size2 :

0.2 mg

price2 :

610

size3 :

1 mg

price3 :

2145

more info or order :

MyBioSource product webpage