catalog number :
MBS551074
products full name :
Rabbit anti Calretinin Polyclonal
products short name :
Calretinin
products name syn :
Rabbit anti Calretinin Polyclonal purified; cal2b; Calretinin; polyclonal; Glycogen synthase kinase
other names :
calretinin isoform 1; Calretinin; 29 kDa calbindin
products gene name :
Calretinin
other gene names :
CALB2; CAB29; CR
uniprot entry name :
CALB2_HUMAN
reactivity :
Human, Mouse, Rat, Cow
purity :
Serum IgG fraction was purified by Protein G affinity chromatography.
form :
Lyophilized from sterile filtered PBS solution at a concentration of 1mg/ml.
storage stability :
The lyophilized antibody is stable for at least 1 year from date of receipt at -20 degree C. Upon reconstitution, this antibody can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months without detectable loss of activity. Avoid repeated freeze/thaw cycles. Shelf Life: >12 months
tested application :
Western Blot (WB), IHC (Immunohistochemistry), ELISA (EIA)
app notes :
ELISA: Use at a concentration range of 1-2ug/ml. Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 ug/ml. IHC: A suitable range of concentrations of this antibody for IHC is 2-10 ug/ml. Immunohistochemical analysis of Calretinin-expressing Human uterine SMC cells.
other info1 :
Source Note: Polyclonal Calretinin antibody was produced from sera of mice immunized with synthetic protein containing Calretinin antigenic determinants.
other info2 :
Reconstitution: A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers
products categories :
Polyclonal
products references :
decrease of the immunohistochemical expression of calcium binding protein ( calretinin ) in the retina of hypercholesterolemic rabbits treated with roziglitazone . Invest. Ophthalmol. Vis. Sci., Apr 2010; 51: 6148. cxcr4 is required for proper regional and laminar distribution of cortical somatostatin-, calretinin -, and neuropeptide y-expressing gabaergic interneurons . Cereb Cortex, Mar 2010; 10.1093/cercor/bhq027. two calretinin -positive gabaergic cell types in layer 2/3 of the mouse neocortex provide different forms of inhibition . Cereb Cortex, Jun 2009; 19: 1345 - 1359. sv40-induced expression of calretinin protects mesothelial cells from asbestos cytotoxicity and may be a key factor contributing to mesothelioma pathogenesis . Am. J. Pathol., Jun 2009; 174: 2324 - 2336. the importance of calretinin in the detection of early alterations of the sensory retina in hypercholesterolemia experimental model . Invest. Ophthalmol. Vis. Sci., Apr 2009; 50: 4941.
ncbi acc num :
NP_001731.2
ncbi gb acc num :
NM_001740.4
ncbi mol weight :
31,540 Da
uniprot summary :
Function: Calretinin is a calcium-binding protein which is abundant in auditory neurons. Tissue specificity: Brain. Sequence similarities: Belongs to the calbindin family.Contains 6 EF-hand domains.