catalog number :
MBS551059
products full name :
Rabbit anti Adrenomedullin Receptor Polyclonal
products short name :
Adrenomedullin Receptor
products name syn :
Rabbit anti Adrenomedullin Polyclonal purified; ADMr; adrenomedullin; gpr182; polyclonal
other names :
G-protein coupled receptor 182; G-protein coupled receptor 182
products gene name :
ADMR
other gene names :
GPR182; ADMR
uniprot entry name :
GP182_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Serum IgG fraction was purified by Protein G affinity chromatography.
form :
Lyophilized from sterile filtered PBS solution at a concentration of 1mg/ml.
storage stability :
The lyophilized antibody is stable for at least 1 year from date of receipt at -20 degree C. Upon reconstitution, this antibody can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months without detectable loss of activity. Avoid repeated freeze/thaw cycles. Shelf Life: >12 months
tested application :
Western Blot (WB), IHC (Immunohistochemistry), ELISA (EIA)
app notes :
ELISA: A suitable range of concentrations of this antibody for IHC is 1-2 ug/ml. Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 ug/ml. IHC: A suitable range of concentrations of this antibody for IHC is 2-10 ug/ml. Immunohistochemistry of FFPE Human lung carcinoma sections expressing ADM receptor. It was used as primary antibody, dilution 1:200.
other info1 :
Source Note: Polyclonal Adrenomedullin Receptor (ADMR) antibody was produced from sera of mice immunized with synthetic protein containing Adrenomedullin Receptor antigenic determinants.
other info2 :
Reconstitution: A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers
products categories :
Polyclonal
products references :
identification of Neuropeptide Y -like conopeptides from the venom of conus betulinus . Acta Biochim Biophys Sin, Jun 2010; 10.1093/abbs/gmq042. Neuropeptide Y directly inhibits neuronal activity in a subpopulation of gonadotropin-releasing hormone-1 neurons via y1 receptors . Endocrinology, Jun 2010; 151: 2736 - 2746. the central and basolateral amygdala are critical sites of Neuropeptide Y /y2 receptor-mediated regulation of anxiety and depression . J. Neurosci., May 2010; 30: 6282 - 6290. estrogen modulates the contribution of Neuropeptide Y to baseline hindlimb blood flow control in female sprague-dawley rats . Am J Physiol Regulatory Integrative Comp Physiol, May 2010; 298: R1351 - R1357. kisspeptin cells in the ewe brain respond to leptin and communicate with Neuropeptide Y and proopiomelanocortin cells . Endocrinology, May 2010; 151: 2233 - 2243.
ncbi acc num :
NP_009195.1
ncbi gb acc num :
NM_007264.3
ncbi mol weight :
45,323 Da
ncbi pathways :
Myometrial Relaxation And Contraction Pathways 198759
uniprot summary :
Function: Orphan receptor. Ref.4. Subcellular location: Cell membrane; Multi-pass membrane protein. Tissue specificity: Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver. Ref.1. Sequence similarities: Belongs to the G-protein coupled receptor 1 family. Caution: Was originally (Ref.1) thought to be a receptor for adrenomedullin.