Rabbit anti CD54 (ICAM1) Polyclonal | MyBioSource MBS551030 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit anti CD54 (ICAM1) Polyclonal

catalog :

MBS551030

quantity :

0.1 mg

price :

280 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS551030

products type :

Antibody

products full name :

Rabbit anti CD54 (ICAM1) Polyclonal

products short name :

CD54 (ICAM1)

products name syn :

Rabbit anti Human CD54 Polyclonal purified; icam1; icam-1; cd54; cd-54; polyclonal; PAb

other names :

intercellular adhesion molecule 1; Intercellular adhesion molecule 1; MALA-2; MyD10

products gene name :

CD54

other gene names :

Icam1; Icam-1; ICAM-1

uniprot entry name :

ICAM1_MOUSE

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

537

purity :

>95%. Purification: Serum IgG fraction was purified by Protein G affinity chromatography.

form :

Lyophilized from 0.2um filtered solution in PBS pH 7.4.

storage stability :

The lyophilized antibody is stable for at least 1 year from date of receipt at -20 degree C. Upon reconstitution, this antibody can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months without detectable loss of activity. Avoid repeated freeze/thaw cycles. Shelf Life: >12 months

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).

app notes :

ELISA: Use at a concentration range of 1-2 ug/ml. WB: Use at a concentration range of 2-10 ug/ml. IHC: A suitable range of concentrations of this antibody for IHC is 2-10 ug/ml.

other info1 :

Source Note: Polyclonal CD54 (ICAM1) antibody was produced from sera of rabbits immunized with synthetic protein containing CD54 antigenic determinants.

other info2 :

Reconstitution: A quick spin of the vial followed by reconstitution in 0.01M PBS pH 7.4 or other dilutents.

products categories :

Polyclonal

products references :

prognostic and predictive impact of expression of the angiogenic markers cd105 and CD31 expression in patients with high risk breast cancer (hrbc). . Cancer Res., Dec 2009; 69: 2154. cd38/ CD31 , the ccl3 and ccl4 chemokines, and cd49d/vascular cell adhesion molecule-1 are interchained by sequential events sustaining chronic lymphocytic leukemia cell survival . Cancer Res., May 2009; 69: 4001 - 4009. circulating monocytes expressing CD31 : implications for acute and chronic angiogenesis . Am. J. Pathol., May 2009; 174: 1972 - 1980. il-7 sustains CD31 expression in human naive cd4+ t cells and preferentially expands the CD31 + subset in a pi3k-dependent manner . Blood, Mar 2009; 113: 2999 - 3007. transcriptional profiling of CD31 + cells isolated from murine embryonic stem cells . Genes Cells, Feb 2009; 14: 243 - 260.

ncbi gi num :

21389311

ncbi acc num :

NP_034623.1

ncbi gb acc num :

NM_010493.2

uniprot acc num :

P13597

ncbi mol weight :

58,844 Da

ncbi pathways :

Adaptive Immunity Signaling Pathway (366714); African Trypanosomiasis Pathway (194387); African Trypanosomiasis Pathway (194323); Cell Adhesion Molecules (CAMs) Pathway (83266); Cell Adhesion Molecules (CAMs) Pathway (480); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889); IL-2 Signaling Pathway (198331); IL-5 Signaling Pathway (198281); Immune System Pathway (366713)

uniprot summary :

ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta. Protein type: Immunoglobulin superfamily; Membrane protein, integral; Cell adhesion. Cellular Component: extracellular space; focal adhesion; cell surface; membrane; integral to plasma membrane; integral to membrane; plasma membrane; immunological synapse; external side of plasma membrane; lipid raft. Molecular Function: integrin binding; protein complex binding. Biological Process: regulation of cell adhesion; virion attachment, binding of host cell surface receptor; negative regulation of calcium ion transport; positive regulation of nitric oxide biosynthetic process; T cell antigen processing and presentation; activation of NF-kappaB transcription factor; positive regulation of cellular extravasation; regulation of cell shape; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell adhesion; leukocyte adhesion; sensory perception of sound; positive regulation of actin filament polymerization; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; positive regulation of vasoconstriction; adhesion to host; cell adhesion mediated by integrin; cell adhesion; acute inflammatory response to antigenic stimulus

size1 :

0.1 mg

price1 :

280 USD

size2 :

0.2 mg

price2 :

385

more info or order :

MyBioSource product webpage