catalog number :
MBS546054
products full name :
Recombinant Human RANTES (rHu RANTES/ CCL5)
products short name :
RANTES (CCL5)
products name syn :
human RANTES (CCL5); Human RANTES/ CCL5
products gene name :
RANTES (CCL5)
sequence :
SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
purity :
>98% by SDS-PAGE and HPLC analyses
form :
Lyophilized from a 0.2um filtered concentrated (1.0mg/ml) solution in 20mM PB, pH 7.4, 100mM NaCl. Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
This lyophilized preparation is stable at 2-8 degree C, but should be kept at -20 degree C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 degree C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degree C to -70 degree C. Avoid repeated freeze/thaw cycles.
other info1 :
Molecular Weight Information: 7.8 kDa, a single non-glycosylated polypeptide chain containing 68 amino acids.
other info2 :
Biological Activity: Measured by its ability to chemoattract human CCR5 transfected BaF3 mouse pro-B cells.The ED50 for this effect is typically 1-5ng/mL. Endotoxin Level: Less than 1EU/mg of rHuRANTES/ CCL5 as determined by LAL method. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apporteioned into working aliquots and stored at < or = -20 Degree C. Further dilutions should be made in appropriate buffered soultions.
products description :
CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells
ncbi acc num :
BAH85797.1