catalog number :
MBS543748
products type :
Blocking Peptide
products full name :
GFAP Peptide
products short name :
[GFAP]
products name syn :
[Astrocyte; FLJ42474; FLJ45472; GFAP; Glial Fibrillary Acidic Protein; Intermediate filament protein antibody]
other names :
[Glial fibrillary acidic protein]
products gene name :
[GFAP]
other gene names :
[GFAP; GFAP]
uniprot entry name :
GFAP_HUMAN
storage stability :
-20°C for long term storage.
tested application :
Immunodepletion, Immunocompetition
app notes :
Immunohistochemistry: 1:200. Western Blot: 1:500
other info1 :
. Immunogen: Synthetic peptide taken within amino acid region 50-100 on human glial fibrillary acidic protein.
products description :
Antigenic Blocking Peptide Glial fibrillary acidic protein. GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
uniprot acc num :
P14136. 226236
uniprot summary :
GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: cytoplasm; cytosol; intermediate filament; intermediate filament cytoskeleton; lysosome; membrane; myelin sheath. Molecular Function: glycoprotein binding; integrin binding; kinase binding; protein binding; structural constituent of cytoskeleton. Biological Process: astrocyte development; Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; intermediate filament organization; neurite regeneration; regulation of neurotransmitter uptake; regulation of protein complex assembly; response to wounding. Disease: Alexander Disease