catalog number :
MBS542697
products type :
Blocking Peptide
products full name :
CD99 Peptide
products short name :
[CD99]
products name syn :
[12E7; CD99; CD99 antigen; CD99 molecule; CD99X; E2 antigen; Ewing Sarcoma; MIC 2X; MIC 2Y; MIC2; MSK5X; Protein MIC2; Surface antigen MIC2; T cell surface glycoprotein E2 antibody]
other names :
[CD99 antigen, isoform CRA_d; CD99 antigen; CD99 antigen; CD99 molecule; 12E7; E2 antigen; Protein MIC2; T-cell surface glycoprotein E2; CD_antigen: CD99]
products gene name :
[CD99]
other gene names :
[CD99; CD99; MIC2; HBA71; MIC2X; MIC2Y; MSK5X; MIC2; MIC2X; MIC2Y]
uniprot entry name :
CD99_HUMAN
concentration :
Quantity: 250 ug; Volume: 100 ul
storage stability :
-20 degree C for long term storage
tested application :
Immunodepletion, Immunocompetition
app notes :
Western Blot: 1:500
other info1 :
Immunogen: Synthetic peptide taken within amino acid region 50-100 to human CD99 antigen.
other info2 :
Determinant: N-epitope. Molecular Function: Cell Adhesion. Structure: Belongs to CD99 family. Subcellular Location: Membrane
products description :
Antigenic Blocking Peptide CD99 Antigen N-epitope. Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity).
ncbi acc num :
EAW98700.1
uniprot acc num :
UPI0000EE42C0
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494)
ncbi summary :
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016]
uniprot summary :
CD99: Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes. Belongs to the CD99 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: Xp22.32 and Yp11.3. Cellular Component: cytoplasm; focal adhesion; integral to plasma membrane; plasma membrane. Biological Process: cell adhesion