catalog number :
MBS542477
products type :
Blocking Peptide
products full name :
Bone marrow stromal cell antigen 1 Peptide
products short name :
[Bone marrow stromal cell antigen 1]
products name syn :
[ADP ribosyl cyclase 2; Bone marrow stromal antigen 1; BST 1; cADPr hydrolase 2; CD157; Cyclic ADP ribose hydrolase 2; NAD(+) nucleosidase antibody]
other names :
[Bone marrow stromal cell antigen 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; bone marrow stromal cell antigen 1; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD_antigen: CD157]
other gene names :
[BST1; BST1; CD157; BST-1; cADPr hydrolase 2]
uniprot entry name :
BST1_HUMAN
form :
Antigenic Blocking Peptide
storage stability :
Storea at -20°C for long term storage
tested application :
Immunodepletion, Immunocompetition
other info1 :
Immunogen: Synthetic peptide
other info2 :
Determinant: N-epitope
products description :
Bone marrow stromal cell antigen 1 Peptide. Synthetic peptide corresponding to amino acids 255-274 of Human Bone marrow stromal cell antigen 1. Peptide was covalently modified
ncbi pathways :
Metabolic Pathways (132956); Nicotinate And Nicotinamide Metabolism Pathway (83014); Nicotinate And Nicotinamide Metabolism Pathway (400); Pancreatic Secretion Pathway (169306); Pancreatic Secretion Pathway (169295); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352)
ncbi summary :
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
uniprot summary :
BST1: Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. Belongs to the ADP-ribosyl cyclase family. Protein type: EC 3.2.2.6; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Hydrolase; Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 4p15. Cellular Component: extrinsic to membrane; plasma membrane. Molecular Function: NAD(P)+ nucleosidase activity; NAD+ nucleosidase activity; phosphorus-oxygen lyase activity; transferase activity. Biological Process: humoral immune response; metabolic process; multicellular organismal development; positive regulation of B cell proliferation