product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit Polyclonal KIRREL Antibody
catalog :
MBS542190
quantity :
0.1 mg
price :
425 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS542190
products type :
Antibody
products full name :
Rabbit Polyclonal KIRREL Antibody
products short name :
[KIRREL]
products name syn :
[FLJ10845; Kin of IRRE like (Drosophila); Kin of IRRE like; Kin of irregular chiasm-like protein 1; Kirrel; MGC129542; MGC129543; NEPH 1; Nephrin like protein 1; Nephrin related antibody]
other names :
[Kin of IRRE-like protein 1; Kin of IRRE-like protein 1; kin of IRRE-like protein 1; kin of IRRE like (Drosophila); Kin of irregular chiasm-like protein 1; Nephrin-like protein 1]
products gene name :
[KIRREL]
other gene names :
[Kirrel; Kirrel; Neph1; Kirrel1; 6720469N11Rik; Kirrel1; Neph1]
uniprot entry name :
KIRR1_MOUSE
clonality :
Polyclonal
host :
Rabbit
reactivity :
Mouse, Rat
sequence length :
789
form :
Affinity Purified Immunoglobulins
concentration :
0.65 mg/ml IgG in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
app notes :
Confocal Microscopy 1:250. Dot Blot: 1:10,000. ELISA: 1:10,000. Immunocytochemistry: 1:250. Immunofluorescence: 1:250. Immunohistochemistry: 1:250. Immunoprecipitation: 1:250. Western Blot: 1:250
other info1 :
Immunogen: Recombinant protein. Expression: Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.
other info2 :
Molecular Function: Myosin Binding. Structure: Interacts with TJP1/ZO-1 and with NPHS2/podocin (via the C-terminus). Interacts with NPHS1/nephrin (via the Ig-like domains); this interaction is dependent on KIRREL glycosylation. Homodimer (via the Ig-like domains). Interacts when tyrosine-phosphorylated with GRB2. Subcellular Location: Cell membrane; Single-pass type I membrane protein
products description :
Affinity Purified Kin of IRRE-like protein 1 Antibody. Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
ncbi gi num :
54036138
ncbi acc num :
Q80W68.1
uniprot acc num :
Q80W68
ncbi mol weight :
69,967 Da
uniprot summary :
KIRREL: Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1. Belongs to the immunoglobulin superfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Cell adhesion. Cellular Component: cell projection membrane; dendritic shaft; integral to membrane; intercellular junction; lipid raft; membrane; perinuclear region of cytoplasm; plasma membrane. Molecular Function: myosin binding; protein binding. Biological Process: cell-cell adhesion; excretion; negative regulation of protein amino acid phosphorylation; positive regulation of actin filament polymerization
size1 :
0.1 mg
price1 :
425 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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