catalog number :
MBS541742
products full name :
Golgin A4 Antibody
products short name :
[Golgin A4]
products name syn :
[256 kDa golgin; 72.1 protein; GCP2; GOLG; GOLGA4; Golgin subfamily A member 4; golgin-240; Golgin-245; MU-RMS-40.18; p230; Protein 72.1; Trans-Golgi p230 antibody]
other names :
[golgin-245; Golgin subfamily A member 4; golgin subfamily A member 4; golgin A4; 256 kDa golgin; Golgin-245; Protein 72.1; Trans-Golgi p230]
other gene names :
[GOLGA4; GOLGA4; GCP2; GOLG; p230; CRPF46; MU-RMS-40.18]
uniprot entry name :
GOGA4_HUMAN
reactivity :
Human, Monkey
form :
Affinity Purified Immunoglobulins
concentration :
0.75 mg/ml IgG in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
app notes :
Dot Blot: 1:10,000. ELISA: 1:10,000. Immunoprecipitation: 1:150. Western Blot: 1:500
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide taken within amino acid region 2025-2075 on human Golgin-245 protein. Expression: Homodimer. Interacts with GTP bound ARL1. Interacts with MACF1. Alternative Nomenclature: 256 kDa golgin antibody. 72.1 protein antibody. GCP2 antibody. GOLG antibody. GOLGA4 antibody. Golgin subfamily A member 4 antibody. golgin-240 antibody. Golgin-245 antibody. MU-RMS-40.18 antibody. p230 antibody. Protein 72.1 antibody. Trans-Golgi p230 antibody.
other info2 :
Molecular Function: GTPase binding; Golgi to plasma membrane protein transport. Structure: Extended rod-like protein with coiled-coil domains. Ctonains 1 GRIP domain. Subcellular Location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus
products categories :
Primary Antibodies; Cell Biology; Organelles; Golgi; Golgin A4 Antibody
products description :
Affinity Purified Golgin-245 Antibody. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1.
ncbi acc num :
AAC51791.1
ncbi mol weight :
262,328 Da
ncbi pathways :
Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway (1383038); Membrane Trafficking Pathway (1269877); Retrograde Transport At The Trans-Golgi-Network Pathway (1383039); Vesicle-mediated Transport Pathway (1269876)
ncbi summary :
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
uniprot summary :
GOLGA4: May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Vesicle. Chromosomal Location of Human Ortholog: 3p22-p21.3. Cellular Component: cytoplasm; cytosol; Golgi apparatus; Golgi membrane; intracellular membrane-bound organelle; nucleoplasm; trans-Golgi network. Molecular Function: GTPase binding; protein binding. Biological Process: Golgi to plasma membrane protein transport; positive regulation of axon extension; protein targeting to Golgi; vesicle-mediated transport