product summary
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company name :
MyBioSource
product type :
antibody
product name :
DWORF Antibody
catalog :
MBS541442
quantity :
0.1 mg
price :
390 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
product information
catalog number :
MBS541442
products type :
Antibody
products full name :
DWORF Antibody
products short name :
[DWORF]
products name syn :
[Dwarf open reading frame; DWORF; Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF; SERCA regulator DWORF antibody]
other names :
[Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF; Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF; Dwarf open reading frame]
products gene name :
[DWORF]
other gene names :
[DWORF; DWORF]
uniprot entry name :
DWORF_MOUSE
clonality :
Polyclonal
host :
Rabbit
reactivity :
Mouse
sequence length :
34
form :
Affinity Purified Immunoglobulins
concentration :
0.65 mg/ml IgG in antibody stabilization buffer
storage stability :
Store at -20 degree C for long term storage
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
app notes :
ELISA: 1:10,000. Immunohistochemistry: 1:50-1:100. Immunoprecipitation: 1:200. Western Blot: 1:500
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Synthetic peptide taken within amino acid reigon 1-30 on mouse Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF protein. Expression: Highly expressed in heart (at protein level). Detected in heart and soleus, a postural muscle group of the hindlimb containing the highest enrichment of slow-twitch muscle fibers. Also expressed in diaphragm, which contains some slow-twitch fibers. Not detected in the quadriceps, a fast-twitch muscle group, or in cardiac atrial muscle. Not expressed in the prenatal heart but gradually increases in abundance postnatally.
other info2 :
Subcellular Location: Sarcoplasmic reticulum membrane; Single-pass membrane protein
products categories :
Primary Antibodies; Signal Transduction; Calcium Binding; DWORF Antibody
products description :
Affinity Purified Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF Antibody. Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle activity. Does not directly stimulates SERCA pump activity. Enhances sarcoplasmic reticulum Ca2+ uptake and myocyte contractility by displacing the SERCA inhibitory peptides sarcolipin (SLN), phospholamban (PLN) and myoregulin (MRLN).
ncbi gi num :
1008808686
ncbi acc num :
P0DN83.1
uniprot acc num :
P0DN83
ncbi mol weight :
3,815 Da
uniprot summary :
DWORF: Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle activity. Does not directly stimulates SERCA pump activity. Enhances sarcoplasmic reticulum Ca(2+) uptake and myocyte contractility by displacing the SERCA inhibitory peptides sarcolipin (SLN), phospholamban (PLN) and myoregulin (MRLN). {ECO:0000250 UniProtKB:P0DN83}. Interacts with ATP2A1/SERCA1. {ECO:0000250 UniProtKB:P0DN83}. Protein type: Membrane protein, integral
size1 :
0.1 mg
price1 :
390 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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