antibody

Dopamine D5 Receptor Antibody BIOTIN-Conjugated

MBS541401

0.1 mg

495 USD

polyclonal

rabbit

biotin

human, mouse, rat

western blot, ELISA, immunoprecipitation, enzyme immunoassay

Antibody

Dopamine D5 Receptor Antibody BIOTIN-Conjugated

[Dopamine D5 Receptor]

[bFGFR, FLJ14326, Fms-like tyrosine kinase, MFR antibody, KAL2, N SAM antibody, OGD antibody, Proto oncogene c-Fgr, Tyrosylprotein kinase, H2, H3, H4, H5 antibody]

[D(1B) dopamine receptor; D(1B) dopamine receptor; D(1B) dopamine receptor; dopamine receptor D5; D(5) dopamine receptor; Dopamine D5 receptor]

[Drd5; Drd5; D5R; Drd-5; Drd1b; Gpcr1]

DRD5_MOUSE

Polyclonal

Rabbit

Human, Mouse, Rat

478

BIOTIN-Conjugated immunoglobulins

0.68 ug/ul in IgG antibody stabilization buffer

-20 degree C for long term storage

ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)

Dot Blot: 1:50,000. ELISA: 1:50,000. Immunoprecipitation: 1:200. Western Blot: 1:1,000-1:1,5000

Immunogen: Synthetic peptide taken within amino acid region 428-478 on mouse Dopamine Receptor D5 protein.

Molecular Function: Dopamine binding; Biological rhythms. Structure: Belongs to G-protein coupled receptor 1 family; Transmembrane helix. Subcellular Location: Cell membrane; Multi-pass membrane

Rabbit Polyclonal Biotin-conjugated D5R Antibody

47115791

Q8BLD9.1

Q8BLD9

Amine Ligand-binding Receptors Pathway (1367063); Calcium Signaling Pathway (83247); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1367055); Dopamine Receptors Pathway (1367066); Dopaminergic Synapse Pathway (469201); Dopaminergic Synapse Pathway (469185); G Alpha (s) Signalling Events Pathway (1367085); GPCR Downstream Signaling Pathway (1367084); GPCR Ligand Binding Pathway (1367054)

DRD5: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. Defects in DRD5 are a cause of benign essential blepharospasm (BEB). BEB is a primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral. Cellular Component: axon; brush border membrane; cell soma; dendrite; dendritic spine; integral to membrane; integral to plasma membrane; membrane; nonmotile primary cilium; plasma membrane. Molecular Function: dopamine binding; dopamine D1 receptor-like receptor activity; dopamine receptor activity; drug binding; G-protein alpha-subunit binding; G-protein coupled receptor activity; signal transducer activity. Biological Process: associative learning; dopamine receptor signaling pathway; dopamine receptor, adenylate cyclase activating pathway; dopamine receptor, phospholipase C activating pathway; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase activating pathway; mating behavior; negative regulation of blood pressure; negative regulation of cell migration; negative regulation of NAD(P)H oxidase activity; negative regulation of protein kinase activity; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; positive regulation of adenylate cyclase activity; positive regulation of cAMP biosynthetic process; regulation of female receptivity; regulation of long-term neuronal synaptic plasticity; regulation of systemic arterial blood pressure by vasopressin; response to amphetamine; response to cocaine; sensitization; signal transduction; synaptic transmission, dopaminergic; transmission of nerve impulse; visual learning; wound healing

0.1 mg

495 USD