product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
WDR5 Antibody
catalog :
MBS540130
quantity :
0.1 mg Affinity-Puri
price :
390 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS540130
products type :
Antibody
products full name :
WDR5 Antibody
products short name :
WDR5
products name syn :
2410008O07Rik; AA408785; AA960360; Big; BIG3; BMP2 induced 3 kb gene protein; MGC114572; OTTHUMP00000162494; SWD3 Set1c WD40 repeat protein homolog; WD repeat-containing protein 5; WD repeat-containing protein BIG-3; WDR 5 antibody
other names :
WD repeat-containing protein 5; BMP2-induced 3-kb gene protein
products gene name :
WDR5
other gene names :
WDR5; BIG3
uniprot entry name :
WDR5_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
334
form :
Affinity Purified
concentration :
0.67 ug/ul in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
app notes :
Dot Blot: 1:10,000. ELISA: 1:10,000. Immunohistochemistry: 1:100. Immunoprecipitation: 1:200. Western Blot: 1:500
other info1 :
Immunogen: Synthetic Peptide taken within amino acid region 150-175 on WDR5 protein.
other info2 :
Molecular Function: Chromatin regulator. Structure: Interacts with PAXBP1; the interaction is direct and links a WDR5-containing histone methyltransferase complex to PAX7 and PAX3. Interacts with HCFC1. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Subcellular Location: Nucleus
products categories :
Primary Antibodies; Epigenetics; Chromatin Modifying Enzymes; Methylation; WDR5 Antibody
products description :
Affinity Purified WD repeat-containing protein 5 Antibody. Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues.
ncbi acc num :
NP_060058.2
uniprot acc num :
P61964
ncbi mol weight :
36,588 Da
uniprot summary :
WDR5: a WD40 repeat protein. May accelerate osteoblast differentiation. Interacts with HCFC1. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 9q34. Cellular Component: histone acetyltransferase complex; histone methyltransferase complex; nucleoplasm; nucleus. Molecular Function: histone acetyltransferase activity (H4-K16 specific); histone lysine N-methyltransferase activity (H3-K4 specific); histone-lysine N-methyltransferase activity; methylated histone residue binding; protein binding. Biological Process: histone H3-K4 methylation; neurite development; skeletal development; transcription, DNA-dependent
size1 :
0.1 mg Affinity-Purified
price1 :
390 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!