product summary
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company name :
MyBioSource
product type :
antibody
product name :
S100 beta Antibody
catalog :
MBS540112
quantity :
0.1 mg Affinity-Puri
price :
425 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS540112
products type :
Antibody
products full name :
S100 beta Antibody
products short name :
S100 beta
products name syn :
NEF; S 100 calcium binding protein beta chain; S 100 protein beta chain; S 100 protein beta subunit; S100 calcium-binding protein B antibody
other names :
Protein S100-P; Protein S100-P; protein S100-P; S100 calcium binding protein P; Migration-inducing gene 9 protein; MIG9; Protein S100-E; S100 calcium-binding protein P
other gene names :
S100P; S100P; MIG9; S100E; MIG9
uniprot entry name :
S100P_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
95
form :
Affinity Purified
concentration :
0.65 ug/ul in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
Confocal Microscopy (CM), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
app notes :
Dot Blot: 1:10,000. ELISA: 1:10,000. Western Blot: 1:500
other info1 :
Immunogen: Full length protein of human S100 beta/beta homodimer. Expression: Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.
other info2 :
Molecular Function: Calcium-dependent protein binding, calcium ion binding, magnesium ion binding. Structure: Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity. Subcellular Location: Nucleus, Cytoplasm, Cell projection ; Microvillus membrane
products categories :
Primary Antibodies; Cell Biology; Cell Cycle; Cell Differentiation; S100 beta Antibody
products description :
May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
ncbi gi num :
134142
ncbi acc num :
P25815.2
uniprot acc num :
P25815
ncbi mol weight :
10,400 Da
ncbi pathways :
Gastric Cancer Network 1 Pathway (760635)
ncbi summary :
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008]
size1 :
0.1 mg Affinity-Purified
price1 :
425 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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