product summary
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company name :
MyBioSource
product type :
antibody
product name :
Phospho-TRP antibody
catalog :
MBS540110
quantity :
0.1-0.15 ml WB Contr
price :
415 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
fruit fly
application :
western blot, immunoprecipitation
more info or order :
product information
catalog number :
MBS540110
products type :
Antibody
products full name :
Phospho-TRP antibody
products short name :
Phospho-TRP
other names :
transient receptor potential, isoform A; Transient receptor potential protein; CG7875 gene product from transcript CG7875-RA; CG7875-PA; CG7875-PB; Cosens-Manning mutant; INAD localization-B; transient photreceptor potential; transient receptor potential; transient receptor potential protein; trp-PA; trp-PB; transient receptor potential
products gene name :
TRP
other gene names :
trp; trp; 559; CG7875; DmelCG7875; DmTRP; dTrp; dTRP; gene B; idl-B; Trp; TRP
uniprot entry name :
TRP_DROME
clonality :
Polyclonal
host :
Rabbit
purity :
Affinity purifed
concentration :
~0.5mg/ml
storage stability :
Shipped at 4 degree C. Store at -20 degree C
tested application :
Western Blot (WB), Immunoprecipitation (IP)
other info1 :
Immunogen: peptide
other info2 :
Preservatives: 0.02% Na3N. Buffer: PO4-buffer/Tris/Glycine, pH 7.4-7.8. PO4-buffer/Tris/Glycine, pH 7.4-7.8
ncbi gi num :
17136554
ncbi acc num :
NP_476768
ncbi gb acc num :
NM_057420.4
uniprot acc num :
P19334
ncbi mol weight :
142,594 Da
ncbi pathways :
Adaptive Immune System Pathway 824474!!Antigen Activates B Cell Receptor Leading To Generation Of Second Messengers Pathway 824484!!Immune System Pathway 824473!!Phototransduction - Fly Pathway 151779!!Phototransduction - Fly Pathway 151778!!Signaling By The B Cell Receptor (BCR) Pathway 824483
uniprot summary :
Function: A light-sensitive calcium channel that is required for inositide-mediated Ca2+ entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca2+ influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling. Trp and trpl act together in the light response, though it is unclear whether as heteromultimers or as distinct units, and are activated by fatty acids and metabolic stress. Also required for olfactory adaptation and may be involved in olfactory system development. Ref.1 Ref.2 Ref.10 Ref.11 Ref.15. Subunit structure: The C-terminus interacts with a PDZ domain of inaD to form the core of the inaD signaling complex. Other members of the complex include norpA (PLC), inaC (PKC), and possibly trpl, ninaC, FKBP59, calmodulin and rhodopsin. Forms homomultimers and heteromultimers with trpl. Interaction with trpl is mediated in part by the N-terminal region and the transmembrane domains. Also interacts, though to a lower extent, with trp-gamma. Ref.8 Ref.9 Ref.13 Ref.16. Subcellular location: Cell membrane; Multi-pass membrane protein . Probable. Note: Localized on plasma membrane loops found at the base of the rhabdomere, in close proximity to the calcium stores. Ref.1 Ref.7 Ref.9 Ref.13. Tissue specificity: Expressed predominantly in the rhabdomeres of photoreceptor cells. Expressed in the third antennal segment and in the olfactory segment at approximately 70 hours after puparium formation during antennal development. Ref.1 Ref.10 Ref.13 Ref.14. Post-translational modification: Phosphorylated by inaC. Ref.12. Sequence similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. [View classification]Contains 2 ANK repeats. Sequence caution: The sequence AAQ22416.1 differs from that shown. Reason: Frameshift at position 721.
size :
0.1-0.15 ml WB Control
price :
415 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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