product summary
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company name :
MyBioSource
product type :
antibody
product name :
Prominin 2 Antibody
catalog :
MBS540106
quantity :
0.1 mg Affinity-Puri
price :
390 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
product information
catalog number :
MBS540106
products type :
Antibody
products full name :
Prominin 2 Antibody
products short name :
Prominin 2
products name syn :
MGC138714; PROM 2; Prominin like protein 2; Prominin related protein; Prominin-2 antibody
other names :
prominin-2 isoform 1; Prominin-2; prominin-2; prominin 2; Prominin-like protein 2; hPROML2
other gene names :
PROM2; PROM2; PROML2; PROML2; PROM-2; hPROML2
uniprot entry name :
PROM2_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
834
form :
Affinity Purified
concentration :
0.65 ug/ul in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
app notes :
Confocal Microscopy 1:100. Dot Blot: 1:2,000. ELISA: 1:2,000. Immunocytochemistry: 1:100. Immunofluorescence: 1:100. Immunohistochemistry: 1:100. Immunoprecipitation: 1:200. Western Blot: 1:500
other info1 :
Immunogen: Synthetic peptide corresponding to Human Prominin 2 amino acids 315-338. Sequence: RTLELGADFSQVPSVDHVLHQLKG. Expression: Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines.
other info2 :
Molecular Function: Cholesterol binding. Subcellular Location: Apical cell membrane, multi-pass membrane protein (Note: Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells).
products categories :
Primary Antibodies; Cancer Research; Tumor Suppressors; Prominin 2 Antibody
ncbi gi num :
260764011
ncbi acc num :
NP_653308.2
ncbi gb acc num :
NM_144707.3
uniprot acc num :
Q8N271
ncbi mol weight :
40,582 Da
ncbi summary :
This gene encodes a member of the prominin family of pentaspan membrane glycoproteins. The encoded protein localizes to basal epithelial cells and may be involved in the organization of plasma membrane microdomains. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
uniprot summary :
PROM2: a multi-pass membrane protein of the prominin family that binds cholesterol. Localizes to the apical and basolateral membranes of epithelial cells. Present in saliva within small membrane particles. Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines. Three alternatively spliced human isoforms have been described. Protein type: Cell surface; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 2q11.1. Cellular Component: apical plasma membrane; basolateral plasma membrane; cell projection; cell surface; cilium; cytoplasmic vesicle; integral to plasma membrane; lipid raft; microvillus; microvillus membrane. Molecular Function: cholesterol binding. Biological Process: negative regulation of pinocytosis; positive regulation of cell projection organization and biogenesis; positive regulation of protein amino acid phosphorylation; regulation of GTPase activity
size1 :
0.1 mg Affinity-Purified
price1 :
390 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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