catalog number :
MBS540101
products full name :
Phospho PDE3A Antibody Affinity Purified
products short name :
Phospho-PDE3A
products name syn :
5''-cyclic phosphodiesterase A; cAMP phosphodiesterase myocardial cGMP inhibited; CGI PDE; CGI PDE A; cGMP inhibited 3' 5' cyclic phosphodiesterase A; Cyclic GMP-inhibited phosphodiesterase A; Human cGMP inhibited cAMP phosphodiesterase mRNA; PDE 3A; Phosphodiesterase 3A; Phosphodiesterase 3A cGMP inhibited antibody
other names :
cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; phosphodiesterase 3A, cGMP inhibited; Cyclic GMP-inhibited phosphodiesterase A; CGI-PDE A
products gene name :
PDE3A
other gene names :
Pde3a; Pde3a; C87899; A930022O17Rik; CGI-PDE A
uniprot entry name :
PDE3A_MOUSE
reactivity :
Chicken, Human, Mouse, Rat
concentration :
1.0-1.25 ug/ul in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
ELISA (EIA), IMM, Western Blot (WB)
app notes :
Dot Blot: 1:10,000. ELISA: 1:10,000. Immunoprecipitation: 1:200. Western Blot: 1:500
other info1 :
Immunogen: Synthetic peptide taken within amino acid region 250-300 on mouse PDE3A protein.
other info2 :
Modification: Phosphorylated. Molecular Function: Hydrolase, 3', 5'-cyclic-AMP phosphodiesterase activity, cAMP binding. Subcellular Location: Membrane; Multipass membrane protein
products categories :
Primary Antibodies; Signal Transduction; Second Messengers; cAMP; Phospho-PDE3A Antibody
products description :
Affinity Purified Phosphorylated cGMP-inhibited 3', 5'-cyclic phosphodiesterase A Antibody. Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Involved in oocyte maturation.
ncbi acc num :
NP_061249.1
ncbi gb acc num :
NM_018779.1
ncbi mol weight :
124,513 Da
ncbi pathways :
G Alpha (s) Signalling Events Pathway (1367085); GPCR Downstream Signaling Pathway (1367084); Hemostasis Pathway (1368135); Morphine Addiction Pathway (552689); Morphine Addiction Pathway (554808); Nitric Oxide Stimulates Guanylate Cyclase Pathway (1368138); Platelet Homeostasis Pathway (1368136); Purine Metabolism Pathway (83144); Purine Metabolism Pathway (672434); Purine Metabolism Pathway (307)
uniprot summary :
PDE3A: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Inhibited by cGMP. Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. Protein type: EC 3.1.4.17; Nucleotide Metabolism - purine; Membrane protein, integral; Membrane protein, multi-pass; Phosphodiesterase. Cellular Component: cytosol; integral to membrane; membrane. Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; cAMP binding; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity. Biological Process: cAMP catabolic process; cAMP-mediated signaling; cGMP-mediated signaling; negative regulation of apoptosis; negative regulation of vascular permeability; oocyte maturation; positive regulation of vascular permeability; regulation of meiosis; response to drug; signal transduction
size1 :
0.1 mg Affinity-Purified