catalog number :
MBS5400735
products type :
Positive Control
products full name :
Myoregulin Positive Control
products short name :
[Myoregulin]
products name syn :
[Myoregulin antibody; Long Intergenic Non-Protein Coding RNA 948 antibody; Muscle Enriched RNA antibody; Muscle Specific antibody; MLN antibody; LINC00948 antibody; MUSER1 antibody; M1 antibody]
other names :
[myoregulin; Myoregulin; myoregulin; myoregulin]
products gene name :
[MLN]
other gene names :
[MRLN; MRLN; M1; MLN; MUSER1; Linc-RAM; LINC00948]
form :
Western Blot Positive Control
concentration :
Empirically set for optimal signal-to-noise ratio.
storage stability :
Store at -20 degree C for long term storage.
tested application :
Western Blot (WB)
other info1 :
Immunogen: Purified protein. Storage Buffer: Prepared in SDS-sample buffer.
ncbi acc num :
NP_001291661
ncbi gb acc num :
NM_001304732.1
ncbi summary :
This gene encodes a small peptide that shares structural similarity to the small peptides sarcolipin and phospholamban, which are key regulators of sarcoplasmic reticulum Ca(2+)-ATPases (SERCAs). This protein is thought to have a similar function to these peptides, regulating Ca(2+) reuptake in the sarcoplasmic reticulum by inhibiting the Ca(2+) pump activity of SERCAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2015]
uniprot summary :
Inhibits the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+, thereby acting as a key regulator of skeletal muscle activity. Its high expression in adult skeletal muscle, suggests that it constitutes the predominant regulator of ATP2A1/SERCA1 in adult skeletal muscle.