catalog number :
MBS540064
products full name :
PDE4 Antibody
products short name :
PDE4
products name syn :
PDE4A; PDE4B; PDE4C; PDE4D; Phosphodiesterase 4; Phosphodiesterase 4A; Phosphodiesterase 4B; Phosphodiesterase 4C; Phosphodiesterase 4D antibody
products gene name :
PDE4
reactivity :
Chicken, Human, Monkey, Mouse, Rat
specificity :
This antibody detects all known PDE4 A and D variants including PDE4A1, A5, Ax, A8 and PDE4D1-D5. It has low affinity for PDE4B variants.
concentration :
0.62 ug/ul in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
app notes :
Confocal Microscopy 1:200. Dot Blot: 1:10,000. ELISA: 1:10,000. Immunocytochemistry: 1:200. Immunofluorescence: 1:200. Immunohistochemistry: 1:200. Immunoprecipitation: 1:200. Western Blot: 1:500-1:1,000
other info1 :
Immunogen: Synthetic peptide common to most PDE4 subtypes: PDE4A, PDE4D, PDE4B. Expression: Low expression during growth and cell aggregation (up to 6 hours), maximally increases after 9 hours of starvation, during the mound stage. Remains expressed at significant levels during the other stages of multicellular development.
other info2 :
Molecular Function: 3', 5'-cyclic-nucleotide phosphodiesterase activity; cAMP catabolic process; signal transduction; Hydrolase. Structure: Belongs to the cyclic nucleotide phosphodiesterase family. Subcellular Location: Cell membrane; Multipass membrane protein
products categories :
Primary Antibodies; Signal Transduction; Regulation; PDE4 Antibody
products description :
Phosphodiesterase 4 Antibody. Phosphodiesterase specific for extracellular cAMP. Involved in the degradation of extracellular cAMP specifically during multicellular development.
size1 :
0.1 mg Affinity-Purified