antibody

proBNP Antibody

MBS540055

0.1 mg Affinity-Puri

390 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, enzyme immunoassay

Antibody

proBNP Antibody

proBNP

BNP 32; BNP; BNP(1-32); BNP(5-29); Brain Natriuretic Peptide 32; Gamma brain natriuretic peptide; Natriuretic peptide precursor type B; NPPB antibody

Natriuretic peptides B; Natriuretic peptides B; natriuretic peptides B; natriuretic peptide B; Gamma-brain natriuretic peptide

proBNP

NPPB; NPPB; BNP; BNP(1-32); BNP-32

ANFB_HUMAN

Polyclonal

Rabbit

Human, Monkey

134

No cross reactivity with proANP.

Affinity Purified

0.8 ug/ul in antibody stabilization buffer

-20 degree C for long term storage

Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

Confocal Microscopy 1:200. Dot Blot: 1:10,000. ELISA: 1:10,000. Immunocytochemistry: 1:200. Immunofluorescence: 1:200. Immunohistochemistry: 1:200. Immunoprecipitation: 1:200. Western Blot: 1:500

Immunogen: Synthetic peptide taken within amino acid region 100-150 on human proBNP. Expression: Is expressed in the brain and atria, however it is expressed at much lower levels than ANP.

Molecular Function: Diuretic hormone activity, Hormone, Vasoactive. Subcellular Location: Secreted

Primary Antibodies; Neuroscience; Neuropeptides & Hormones; proBNP Antibody

Affinity Purified Gamma-brain natriuretic peptide Antibody. A cardiac hormone that may also serve as a paracrine antifibrotic factor in the heart. Also functions in cardiovascular homeostasis via natriuresis, diuresis, vasorelaxation, and the inhibition of renin and aldosterone secretion.

113836

P16860.1

P16860

14,726 Da

MicroRNAs In Cardiomyocyte Hypertrophy Pathway (198784); CGMP-PKG Signaling Pathway (983748); CGMP-PKG Signaling Pathway (985584)

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]

NPPB: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. Belongs to the natriuretic peptide family. Protein type: Secreted; Hormone; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1p36.2. Cellular Component: extracellular region; extracellular space; protein complex. Molecular Function: diuretic hormone activity; hormone activity; protein binding; receptor binding. Biological Process: body fluid secretion; cell surface receptor linked signal transduction; cGMP biosynthetic process; negative regulation of angiogenesis; negative regulation of cell growth; receptor guanylyl cyclase signaling pathway; regulation of blood pressure; regulation of vascular permeability; regulation of vasodilation

0.1 mg Affinity-Purified

390 USD