antibody

P2Y1 Antibody Affinity Purified

MBS540047

0.1 mg Affinity-Puri

390 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, enzyme immunoassay

Antibody

P2Y1 Antibody Affinity Purified

P2Y1

ATP receptor; P2 purinoceptor subtype Y1; P2RY1; P2RY1_HUMAN; P2Y purinoceptor 1; P2Y1; P2Y1 purinoceptor; Platelet ADP receptor; Purinergic receptor; Purinergic receptor P2Y G protein coupled 1; Purinergic receptor P2Y1 antibody

P2Y purinoceptor 1; P2Y purinoceptor 1; P2Y purinoceptor 1; purinergic receptor P2Y1; ATP receptor; Purinergic receptor

P2Y1

P2ry1; P2ry1; P2y; P2y1; P2Y1

P2RY1_RAT

Polyclonal

Rabbit

Cat, Human, Mouse, Rat

373

Affinity Purified

0.55-0.85 ug/ul in antibody stabilization buffer

-20 degree C for long term storage

ELISA (EIA), Western Blot (WB)

Dot Blot: 1:10,000. ELISA: 1:10,000. Western Blot: 1:500

Immunogen: Synthetic peptide taken within amino acid region 360-410 on rat P2Y1. Expression: Is found to be expressed in muscle, heart, liver, kidney, lung, brain, spleen. Not expressed in testis.

Molecular Function: G-protein coupled receptor, Transducer, Receptor. Subcellular Location: Cell membrane; Multipass membrane protein

Primary Antibodies; Signal Transduction; G-Protein Coupled Receptors; P2Y1 Antibody

Affinity Purified P2Y purinoceptor 1 Antibody. Serves as a receptor for extracellular adenine nucleotides, for example ATP and ADP. It may mediate some effects of extracellular ATP on insulin secretion in the pancreatic islets.

1352695

P49651.1

P49651

42,322 Da

ADP Signalling Through P2Y Purinoceptor 1 Pathway (1376404); Class A/1 (Rhodopsin-like Receptors) Pathway (1376996); G Alpha (q) Signalling Events Pathway (1377029); GPCR Downstream Signaling Pathway (1377025); GPCR Ligand Binding Pathway (1376995); GPCRs, Class A Rhodopsin-like Pathway (198500); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1377042); Hemostasis Pathway (1376390); Neuroactive Ligand-receptor Interaction Pathway (83445); Neuroactive Ligand-receptor Interaction Pathway (462)

G protein-coupled receptor for extracellular ATP; plays a role in ischemic preconditioning (IPC) in heart [RGD, Feb 2006]

P2RY1: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR. Cellular Component: apical plasma membrane; basolateral plasma membrane; cell surface; dendrite; integral to membrane; mitochondrion; plasma membrane; postsynaptic membrane. Molecular Function: A1 adenosine receptor binding; ADP binding; ADP-activated nucleotide receptor activity; ATP binding; ATP-activated nucleotide receptor activity; protein heterodimerization activity; purinergic nucleotide receptor activity, G-protein coupled. Biological Process: adenosine receptor signaling pathway; aging; eating behavior; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; glial cell migration; negative regulation of binding; platelet activation; positive regulation of hormone secretion; positive regulation of inositol trisphosphate biosynthetic process; positive regulation of ion transport; positive regulation of protein amino acid phosphorylation; positive regulation of transcription from RNA polymerase II promoter; regulation of receptor activity; regulation of vasodilation; response to mechanical stimulus; sensory perception of pain; wound healing

0.1 mg Affinity-Purified

390 USD