catalog number :
MBS540037
products full name :
IFI27 Antibody
products short name :
IFI27
products name syn :
2310061N23Rik; FAM14D; IFI 27; Interferon alpha induced 11.5 kDa protein; Interferon inducible protein 27; interferon-stimulated gene 12; ISG 12; ISG12A; P27 antibody
other names :
interferon alpha-inducible protein 27, mitochondrial isoform 2; Interferon alpha-inducible protein 27, mitochondrial; interferon alpha-inducible protein 27, mitochondrial; interferon alpha inducible protein 27; Interferon alpha-induced 11.5 kDa protein; Interferon-stimulated gene 12a protein; ISG12(a)
products gene name :
IFI27
other gene names :
IFI27; IFI27; P27; ISG12; FAM14D; ISG12A; p27; ISG12(a)
uniprot entry name :
IFI27_HUMAN
reactivity :
Human, Monkey
concentration :
0.50-0.75 ug/ul in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin, Immunoprecipitation (IP), Western Blot (WB)
app notes :
Dot Blot: 1:100,000. ELISA: 1:100,000. Immunoprecipitation: 1:150. Western Blot: 1:500
other info1 :
Immunogen: Synthetic peptide: multiple antigenic peptide (8 branch) corresponding to amino acids 2-13 of Human IFI27. Sequence: EASALTSSAVTS. Expression: Up-regulated by interferons
other info2 :
Determinant: N-epitope. Molecular Function: Lamin binding; RNA polymerase II activating transcription factor binding. Structure: Belongs to the IFI6/IFI27 family. Subcellular Location: Mitochondrion; Multi-pass membrane protein
products categories :
Primary Antibodies; Immunology; Innate Immunity; Macrophage / Inflammation; IFI27 Antibody
products description :
Affinity Purified Interferon, alpha-inducible protein 27 Antibody N-epitope. Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.
ncbi acc num :
NP_005523.3
ncbi gb acc num :
NM_005532.4
ncbi mol weight :
11,268 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway (1269310); Immune System Pathway (1269170); Interferon Signaling Pathway (1269311); Interferon Alpha/beta Signaling Pathway (1269312)
uniprot summary :
IFI27: Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. Belongs to the IFI6/IFI27 family. Protein type: Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 14q32. Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrion; nuclear inner membrane. Molecular Function: lamin binding. Biological Process: caspase activation; negative regulation of transcription from RNA polymerase II promoter; regulation of protein export from nucleus
size1 :
0.1 mg Affinity-Purified