catalog number :
MBS540025
products full name :
Glucose-6-Phosphate, catalytic subunit Antibody Affinity Purified
products short name :
Glucose-6-Phosphate
products name syn :
AW107337; G-6-Pase; g6pc; G6PT; Glucose-6-phosphatase alpha; GSD1; GSD1a; MGC163350; MGC93613; RP23-281C18.19 antibody
other names :
Glucose-6-phosphatase 2; Islet-specific glucose-6-phosphatase catalytic subunit-related protein
other gene names :
G6pc2; Igrp; G-6-Pase 2; G6Pase 2
uniprot entry name :
G6PC2_MOUSE
reactivity :
Human, Monkey, Mouse, Rat
concentration :
0.55-0.65 ug/ul in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
app notes :
ELISA: 1:10,000. Immunoprecipitation: 1:200. Western Blot: 1:500
other info1 :
Immunogen: Synthetic peptide taken within amino acid region 80-130 on G6PC2 protein, and common in larger variant of glucose 6 phosphatase. Expression: Specifically expressed in pancreatic islet cells, in particular those of beta-cell origin. Not detected in testis, kidney, muscle, liver, lung, spleen, brain, pituitary, gastric fundus or heart.
other info2 :
Molecular Function: Gluconeogenesis. Structure: Belongs to the glucose-6-phosphatase family. Subcellular Location: Endoplasmic Reticulum Membrane; Multi-pass membrane protein
products categories :
Primary Antibodies; Cell Biology; Glucose-6-Phosphate, catalytic subunit Antibody
products description :
Affinity Purified Glucose-6-phosphoate catalytic 2 Antibody. May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis.
ncbi mol weight :
17,894 Da
uniprot summary :
G6PC2: May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis. Belongs to the glucose-6-phosphatase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Carbohydrate Metabolism - starch and sucrose; Endoplasmic reticulum; Membrane protein, multi-pass; Transporter; Carbohydrate Metabolism - galactose; Membrane protein, integral; Phosphatase (non-protein); Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 3.1.3.9; Transporter, SLC family. Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to membrane; membrane. Molecular Function: glucose-6-phosphatase activity; hydrolase activity. Biological Process: dephosphorylation; gluconeogenesis; glucose 6-phosphate metabolic process; glucose homeostasis; regulation of insulin secretion
size1 :
0.1 mg Affinity-Purified