catalog number :
MBS5400185
products full name :
TSH beta Antibody BIOTIN-Conjugated
products short name :
[TSH beta]
products name syn :
[CHNG4; Thyroid stimulating hormone beta subunit; Thyrotropin beta subunit; TSHB antibody]
other names :
[Thyroid stimulating hormone, beta; Thyrotropin subunit beta; thyrotropin subunit beta; thyroid stimulating hormone beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain; INN: Thyrotropin alfa]
products gene name :
[TSH]
other gene names :
[TSHB; TSHB; TSH-B; TSH-BETA; TSH-B; TSH-beta]
uniprot entry name :
TSHB_HUMAN
reactivity :
Human, Mouse, Rat
concentration :
0.63-0.69 ug/ul in antibody stabilization buffer
storage stability :
-20 degree C for long term storage
tested application :
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Confocal Microscopy 1:250. Dot Blot: 1:50,000. ELISA: 1:50,000. Immunocytochemistry: 1:250. Immunofluorescence: 1:250. Immunohistochemistry: 1:250. Western Blot: 1:500
other info1 :
Immunogen: Synthetic peptide corresponding to unique amino acid sequence on human TSH beta chain protein.
other info2 :
Determinant: C-epitope. Molecular Function: hormone activity. Subcellular Location: Secreted
products description :
BIOTIN-Conjugated Thyroid stimulating hormone, beta Antibody C-epitope. Indespensable for the control of thyroid structure and metabolism.
ncbi acc num :
AAH69298.1
ncbi mol weight :
10,624 Da
ncbi summary :
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
uniprot summary :
TSHB: Indispensable for the control of thyroid structure and metabolism. Belongs to the glycoprotein hormones subunit beta family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1p13. Cellular Component: extracellular region. Molecular Function: hormone activity. Biological Process: anatomical structure morphogenesis; cell-cell signaling; G-protein coupled receptor protein signaling pathway; peptide hormone processing; response to calcium ion; response to estrogen stimulus; response to vitamin A. Disease: Hypothyroidism, Congenital, Nongoitrous, 4