product summary
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company name :
MyBioSource
product type :
protein
product name :
Cardiotrophin 1 protein (Mouse)
catalog :
MBS539527
quantity :
0.01 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS539527
products type :
Recombinant Protein
products full name :
Cardiotrophin 1 protein (Mouse)
products short name :
Cardiotrophin 1
products name syn :
Cardiotrophin-1; Cardiotrophin 1 protein; Cardiotrophin-1 protein; CT-1 protein; Cardiotrophin 1
other names :
cardiotrophin-1 isoform 1; Cardiotrophin-1; cardiotrophin-1; cardiotrophin 1
other gene names :
CTF1; CTF1; CT1; CT-1; CT-1
uniprot entry name :
CTF1_HUMAN
host :
Mouse
sequence length :
201
sequence :
Region of Cardiotrophin 1 protein corresponding to amino acids SQREGSLEDH QTDSSISFLP HLEAKIRQTH NLARLLTKYA EQLLEEYVQQ QGEPFGLPGF SPPRLPLAGL SGPAPSHAGL PVSERLRQDA AALSVLPALL DAVRRRQAEL NPRAPRLLRS LEDAARQVRA LGAAVETVLA ALGAAARGPG PEPVTVATLF TANSTAGIFS AKVLGFHVCG LYGEWVSRTE GDLGQLVPGG VA.
purity :
> 98% pure
form :
Supplied as a lyophilized powder
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Protein Type: Recombinant. Biological Significance: CT-1 is a member of the IL6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL11, IL6 and possibly NNT-1/ BCSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Bioactivity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was 1 x 10^6units/mg. Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
other info2 :
Expression System: E Coli
products categories :
Cardiac Markers
products description :
Purified recombinant Mouse Cardiotrophin 1 protein
ncbi gi num :
4503121
ncbi acc num :
NP_001321.1
ncbi gb acc num :
NM_001330.3
uniprot acc num :
Q16619
ncbi mol weight :
21.3 kDa
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); MicroRNAs In Cardiomyocyte Hypertrophy Pathway (198784); Physiological And Pathological Hypertrophy Of The Heart Pathway (920978)
ncbi summary :
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
uniprot summary :
CTF1: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytokine. Chromosomal Location of Human Ortholog: 16p11.2. Cellular Component: extracellular space; extracellular region. Molecular Function: leukemia inhibitory factor receptor binding; cytokine activity. Biological Process: cell proliferation; nervous system development; muscle development; cell-cell signaling; leukemia inhibitory factor signaling pathway; positive regulation of cell proliferation; neuron development
size1 :
0.01 mg
price1 :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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