catalog number :
MBS539503
products type :
Recombinant Protein
products full name :
TL1A protein
products short name :
TL1A
products name syn :
VEGI protein; TNFSF15 protein; TL-1A protein; TLA 1; TL1A; TLA 1 protein; TLA-1; TLA-1 protein
other names :
Thaumatin-like protein 1a; Thaumatin-like protein 1a; Mdtl1; Pathogenesis-related protein 5a; PR-5a; Allergen: Mal d 2
products gene name :
TL1A
other gene names :
TL1; TL; PR-5a
uniprot entry name :
TP1A_MALDO
sequence :
Region of TL1A protein corresponding to amino acids QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVTDS YPEPTQLLMG TKSVCEVGSN WFQPIYLGAM FSLQEGDKLM VNVSDISLVD YTKEDKTFFG AFLL.
form :
Supplied as a lyophilized powder
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Protein Type: Recombinant. Biological Significance: TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon. TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NF kb activation, caspase activity, and apoptosis in responding cell lines. TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6. Bioactivity: Determined by its ability to stimulate IFN-gamma production by human PBMC using a concentration range of 10.0-100.0 ng/ml. Note: Results may vary with PBMC donors. Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
other info2 :
Expression System: E Coli
products categories :
Cytokines & Growth Factors
products description :
Purified recombinant Human TL1A protein
ncbi mol weight :
22.0 kDa