product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Maspin protein
catalog :
MBS539489
quantity :
0.02 mg
price :
320 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS539489
products type :
Recombinant Protein
products full name :
Maspin protein
products short name :
Maspin
products name syn :
Protease inhibitor 5 protein; SerpinB5 protein
other names :
maspin; Serpin B5; serpin B5; PI-5; peptidase inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serpin peptidase inhibitor, clade B (ovalbumin), member 5; Maspin; Peptidase inhibitor 5
other gene names :
SERPINB5; SERPINB5; PI5; maspin; PI5; PI-5
uniprot entry name :
SPB5_HUMAN
host :
E.coli
reactivity :
Human
purity :
>97% pure by SDS PAGE and HPLC
form :
Supplied as a lyophilized powder
storage stability :
Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
other info1 :
Residues: Region of KGF protein corresponding to amino acids MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP.
other info2 :
Endotoxin Level: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
products categories :
Proteases, Inhibitors, Proteins; Native & Recombinant Proteins; Recombinant
products description :
Purified recombinant Human Maspin protein. Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth, invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the ability of Maspin to inhibit angiogenesis and to preferentially promote apoptosis of tumor cells.
ncbi gi num :
453369
ncbi acc num :
AAA18957.1
uniprot acc num :
P36952
ncbi mol weight :
42.2 kDa
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!Direct P53 Effectors Pathway 137939!!P53 Signaling Pathway 83055!!P53 Signaling Pathway 465
uniprot summary :
Function: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. Subunit structure: Interacts with IRF6. Ref.7. Subcellular location: Secreted extracellular space. Tissue specificity: Normal mammary epithelial cells. Sequence similarities: Belongs to the serpin family. Ov-serpin subfamily.
size :
0.02 mg
price :
320 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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