product summary
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company name :
MyBioSource
product type :
protein
product name :
TIMP1 protein
catalog :
MBS539447
quantity :
0.01 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS539447
products type :
Recombinant Protein
products full name :
TIMP1 protein
products short name :
TIMP1
products name syn :
TIMP 1 protein; TIMP-1 protein; TIMP-1; Tissue inhibitor of metalloproteinases: Fibroblast collagenase inhibitor; Erythroid-potentiating activity protein; TIMP1; TIMP 1
other names :
TIMP-1; Metalloproteinase inhibitor 1; metalloproteinase inhibitor 1; Embryogenin-1; EG-1; Tissue inhibitor of metalloproteinases 1; TIMP-1
products gene name :
TIMP1
other gene names :
TIMP1; TIMP1; EG-1; TIMP-1
uniprot entry name :
TIMP1_BOVIN
host :
Human
sequence length :
207
sequence :
Region of TIMP1 protein corresponding to amino acids CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIA.
purity :
> 95% pure
form :
Supplied as a lyophilized powder
concentration :
10ug/vial; lyohpilized
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Protein Type: Recombinant. Biological Significance: TIMP1 is an extracellular inhibitor of MMPs (see above) including MMP1, 2, 3, 7, 8, 9, 10, 11, 12, 13, and 16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors. Bioactivity: TIMP1 activity was measured by its ability to inhibit human MMP-1 induced hydrolysis of a chromogenic peptide substrate at room temperature. Half maximal inhibition was obtained at a TIMP-1 concentration of approximately 0.5 ug/ml, when using an MMP-1 concentration of 1.6 ug/ml. Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
other info2 :
Expression System: E Coli
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Purified recombinant Human TIMP1 protein
ncbi gi num :
546974
ncbi acc num :
AAB30892.1
uniprot acc num :
P20414
ncbi mol weight :
20.6 kDa
ncbi pathways :
Activation Of Matrix Metalloproteinases Pathway (1176091); Degradation Of The Extracellular Matrix Pathway (1176090); Extracellular Matrix Organization Pathway (1176077); HIF-1 Signaling Pathway (695207); Hemostasis Pathway (1176291); Matrix Metalloproteinases Pathway (198565); Platelet Activation, Signaling And Aggregation Pathway (1176301); Platelet Degranulation Pathway (1176318); Response To Elevated Platelet Cytosolic Ca2+ Pathway (1176316)
size1 :
0.01 mg
price1 :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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