This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
protein
product name :
PAFAH protein
catalog :
MBS539396
quantity :
0.02 mg
price :
310 USD
product information
catalog number :
MBS539396
products type :
Recombinant Protein
products full name :
PAFAH protein
products short name :
PAFAH
products name syn :
PAF 2-acylhydrolase protein; PAF acetylhydrolase protein; LDL-associated phospholipase A2 protein; LDL-PLA2 protein; 2-acetyl-1-alkylglycerophosphocholine esterase protein; 1-alkyl-2-acetylglycerophosphocholine esterase protein
other names :
platelet-activating factor acetylhydrolase; platelet-activating factor acetylhydrolase
products gene name :
PAFAH
other gene names :
PLA2G7; PAF-AH; Lp-PLA2
host :
Human
sequence length :
436
sequence :
Region of PAFAH protein corresponding to amino acids FDWQYINPVA HMKSSAWVNK IQVLMAAASF GQTKIPRGNG PYSVGCTDLM FDHTNKGTFL RLYYPSQDND RLDTLWIPNK EYFWGLSKFL GTHWLMGNIL RLLFGSMTTP ANWNSPLRPG EKYPLVVFSH GLGAFRTLYS AIGIDLASHG FIVAAVEHRD RSASATYYFK DQSAAEIGDK SWLYLRTLKQ EEETHIRNEQ VRQRAKECSQ ALSLILDIDH GKPVKNALDL KFDMEQLKDS IDREKIAVIG HSFGGATVIQ TLSEDQRFRC GIALDAWMFP LGDEVYSRIP QPLFFINSEY FQYPANIIKM KKCYSPDKER KMITIRGSVH QNFADFTFAT GKIIGHMLKL KGDIDSNVAI DLSNKASLAF LQKHLGLHKD FDQWDCLIEG DDENLIPGTN INTTNQHIML QNSSGIEKYN.
purity :
> 95% pure
form :
Supplied as a lyophilized powder
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Protein Type: Recombinant. Biological Significance: Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet Activating Factor Acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the ?sn2? ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL particles to induce the hydrolysis of LDL associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids. Bioactivity: Measured by its ability to cleave a PAF analog in a chromogenic substrate linked assay. At a PAF-AH concentration of 10.0 ug/ml, 50% cleavage was achieved at an incubation time of approximately 2 minutes. Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
other info2 :
Expression System: 293 cells
products categories :
Immunology
products description :
Purified recombinant Human PAFAH protein
ncbi gi num :
163915175
ncbi acc num :
NP_001106484.1
ncbi gb acc num :
NM_001113013.1
ncbi mol weight :
47-55 kDa
ncbi pathways :
Biosynthesis Of Antibiotics Pathway 1146434!!Ether Lipid Metabolism Pathway 84416!!Ether Lipid Metabolism Pathway 365!!Metabolic Pathways 132936!!Metabolism Of Proteins Pathway 1181766!!Peptide Hormone Metabolism Pathway 1181820!!Synthesis, Secretion, And Deacylation Of Ghrelin Pathway 1181822
size :
0.02 mg
price :
310 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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