catalog number :
MBS538290
products type :
Recombinant Protein
products full name :
Activin A protein
products short name :
Activin A
products name syn :
Activin beta-A protein; Inhibin beta-A protein
sequence :
Region of Activin protein corresponding to amino acids GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS.
form :
Lyophilized from 10 mM Citric Acid pH 3.0. Reconstitute in water to a concentration of 0.5 mg/ml. Do not vortex.
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Protein Type: Recombinant. Biological Significance: Activin A is a TGF beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF beta antagonist, Follistatin. Bioactivity: The ED50 as determined by its ability to inhibit the proliferation of Mouse MPC-11 cells is 2 ng/ml, corresponding to a specific activity of 5 x 10^5 units/mg. Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
other info2 :
Expression System: Hi-5 cells
products categories :
Cytokines & Growth Factors
products description :
Purified recombinant Human Activin A protein